Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0133 | 0.1013 | 0.1013 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0067 | 0.0165 | 0.1625 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0103 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.097 | 0.2917 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0133 | 0.1013 | 0.1013 |
Echinococcus multilocularis | geminin | 0.0153 | 0.127 | 0.127 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0133 | 0.1013 | 1 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0133 | 0.1013 | 0.1013 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.3327 | 1 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0133 | 0.1013 | 1 |
Schistosoma mansoni | glutaminase | 0.0247 | 0.2473 | 0.2473 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0133 | 0.1013 | 0.3045 |
Schistosoma mansoni | hypothetical protein | 0.0153 | 0.127 | 0.127 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0103 | 0.0628 | 0.6204 |
Entamoeba histolytica | aminopeptidase, putative | 0.0103 | 0.0628 | 0.6204 |
Echinococcus granulosus | geminin | 0.0153 | 0.127 | 0.127 |
Brugia malayi | cell division control protein 2 homolog | 0.0133 | 0.1013 | 0.2672 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0103 | 0.0628 | 0.6204 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0133 | 0.1013 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0103 | 0.0628 | 0.6204 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0103 | 0.0628 | 0.0628 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0133 | 0.1013 | 0.4096 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0165 | 0.0495 |
Echinococcus multilocularis | aminopeptidase N | 0.0349 | 0.379 | 0.379 |
Giardia lamblia | Kinase, CMGC CDK | 0.0133 | 0.1013 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0133 | 0.1013 | 0.1013 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0133 | 0.1013 | 1 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0103 | 0.0628 | 0.6204 |
Giardia lamblia | Kinase, CMGC CDK | 0.0133 | 0.1013 | 1 |
Echinococcus granulosus | aminopeptidase N | 0.0349 | 0.379 | 0.379 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0133 | 0.1013 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0103 | 0.0628 | 0.0628 |
Echinococcus granulosus | cyclin dependent kinase | 0.0133 | 0.1013 | 0.1013 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0133 | 0.1013 | 0.1013 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0278 | 0.2873 | 0.5 |
Mycobacterium ulcerans | glutaminase | 0.0247 | 0.2473 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.2471 | 0.7429 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0133 | 0.1013 | 0.3045 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0283 | 0.2935 | 0.8823 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0103 | 0.0628 | 0.0628 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0833 | 1 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0103 | 0.0628 | 0.0628 |
Brugia malayi | Peptidase family M1 containing protein | 0.0349 | 0.379 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0103 | 0.0628 | 0.0628 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0103 | 0.0628 | 0.2541 |
Brugia malayi | glutaminase DH11.1 | 0.0247 | 0.2473 | 0.6524 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0133 | 0.1013 | 0.4096 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0103 | 0.0628 | 0.0628 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0103 | 0.0628 | 0.2541 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0103 | 0.0628 | 0.0628 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0133 | 0.1013 | 0.4096 |
Loa Loa (eye worm) | glutaminase | 0.0247 | 0.2473 | 0.7433 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0133 | 0.1013 | 0.1013 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0133 | 0.1013 | 1 |
Brugia malayi | Peptidase family M1 containing protein | 0.0103 | 0.0628 | 0.1658 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0103 | 0.0628 | 0.6204 |
Brugia malayi | hypothetical protein | 0.0103 | 0.0628 | 0.1658 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0133 | 0.1013 | 0.1013 |
Schistosoma mansoni | family M1 non-peptidase homologue (M01 family) | 0.0067 | 0.0165 | 0.0165 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0103 | 0.0628 | 0.0628 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0833 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0133 | 0.1013 | 1 |
Plasmodium falciparum | protein kinase 5 | 0.0133 | 0.1013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0165 | 0.0495 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0133 | 0.1013 | 0.1013 |
Onchocerca volvulus | 0.0103 | 0.0628 | 0.1658 | |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0133 | 0.1013 | 0.3045 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0133 | 0.1013 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0133 | 0.1013 | 1 |
Loa Loa (eye worm) | aminopeptidase N | 0.0103 | 0.0628 | 0.1889 |
Brugia malayi | Protein kinase domain containing protein | 0.0133 | 0.1013 | 0.2672 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0103 | 0.0628 | 0.0628 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0103 | 0.0628 | 0.0628 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0133 | 0.1013 | 0.1013 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0133 | 0.1013 | 1 |
Trichomonas vaginalis | glutaminase, putative | 0.0247 | 0.2473 | 1 |
Plasmodium vivax | protein kinase Crk2 | 0.0133 | 0.1013 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0153 | 0.127 | 0.127 |
Loa Loa (eye worm) | glutaminase 2 | 0.0247 | 0.2473 | 0.7433 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0103 | 0.0628 | 0.6204 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0103 | 0.0628 | 0.0628 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0103 | 0.0628 | 0.6204 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0103 | 0.0628 | 0.6204 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0133 | 0.1013 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0067 | 0.0165 | 0.0165 |
Onchocerca volvulus | 0.0349 | 0.379 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.