Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CK1 family protein kinase | 0.0037 | 0 | 0.5 |
Plasmodium falciparum | casein kinase 1 | 0.0037 | 0 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.0037 | 0 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.0037 | 0 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.0037 | 0 | 0.5 |
Trypanosoma cruzi | casein kinase, delta isoform, putative | 0.0037 | 0 | 0.5 |
Loa Loa (eye worm) | protein kinase domain-containing protein | 0.0058 | 1 | 1 |
Entamoeba histolytica | casein kinase 1, putative | 0.0037 | 0 | 0.5 |
Giardia lamblia | Kinase, CK1 Casein kinase | 0.0037 | 0 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.0037 | 0 | 0.5 |
Echinococcus multilocularis | casein kinase I gamma | 0.0058 | 1 | 1 |
Echinococcus granulosus | casein kinase I gamma | 0.0058 | 1 | 1 |
Trypanosoma brucei | casein kinase I, isoform 2 | 0.0037 | 0 | 0.5 |
Plasmodium vivax | casein kinase 1, putative | 0.0037 | 0 | 0.5 |
Toxoplasma gondii | casein kinase I | 0.0037 | 0 | 0.5 |
Loa Loa (eye worm) | casein kinase | 0.0058 | 0.9653 | 0.9653 |
Entamoeba histolytica | casein kinase, putative | 0.0037 | 0 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.0037 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0058 | 1 | 1 |
Trypanosoma cruzi | casein kinase, putative | 0.0037 | 0 | 0.5 |
Onchocerca volvulus | 0.0037 | 0 | 0.5 | |
Trichomonas vaginalis | CK1 family protein kinase | 0.0037 | 0 | 0.5 |
Leishmania major | casein kinase, putative | 0.0037 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.