Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0129 | 0.3923 | 0.3115 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0074 | 0.1174 | 0.5 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0203 | 0.7613 | 0.8549 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0074 | 0.1174 | 0.5 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0074 | 0.1174 | 0.5 |
Brugia malayi | hypothetical protein | 0.0074 | 0.1174 | 0.1174 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.0084 | 0.1693 | 1 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0079 | 0.1415 | 0.1415 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0074 | 0.1174 | 0.5 |
Echinococcus granulosus | aminopeptidase N | 0.0251 | 1 | 1 |
Onchocerca volvulus | Matrilysin homolog | 0.0079 | 0.1415 | 0.1415 |
Onchocerca volvulus | 0.0074 | 0.1174 | 0.1174 | |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0074 | 0.1174 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0074 | 0.1174 | 0.1174 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0074 | 0.1174 | 0.5 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0074 | 0.1174 | 0.5 |
Echinococcus multilocularis | aminopeptidase N | 0.0251 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.6318 | 0.683 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.8705 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0074 | 0.1174 | 0.5 |
Onchocerca volvulus | 0.0251 | 1 | 1 | |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0129 | 0.3923 | 0.3115 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0074 | 0.1174 | 0.5 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0074 | 0.1174 | 0.5 |
Loa Loa (eye worm) | matrixin family protein | 0.0086 | 0.1769 | 0.079 |
Loa Loa (eye worm) | matrixin family protein | 0.0079 | 0.1415 | 0.0321 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0074 | 0.1174 | 0.6933 |
Brugia malayi | Matrixin family protein | 0.0086 | 0.1769 | 0.1769 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0074 | 0.1174 | 0.6933 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0074 | 0.1174 | 0.5 |
Entamoeba histolytica | aminopeptidase, putative | 0.0074 | 0.1174 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.