Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | phosphatidylglycerophosphate synthase, putative | 0.0641 | 0 | 0.5 |
Brugia malayi | Phospholipase D. Active site motif family protein | 0.0755 | 0.034 | 0.034 |
Onchocerca volvulus | Putative phospholipase D | 0.0755 | 0.034 | 0.5 |
Echinococcus multilocularis | phospholipase D1 | 0.4001 | 1 | 1 |
Plasmodium falciparum | mitochondrial cardiolipin synthase, putative | 0.0641 | 0 | 0.5 |
Chlamydia trachomatis | phospholipase D endonuclease family protein | 0.0641 | 0 | 0.5 |
Entamoeba histolytica | phospholipase D, putative | 0.4001 | 1 | 1 |
Loa Loa (eye worm) | phospholipase D | 0.0755 | 0.034 | 0.042 |
Chlamydia trachomatis | phospholipase D endonuclease family protein | 0.0641 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2606 | 0.5848 | 0.7225 |
Schistosoma mansoni | phospholipase D | 0.4001 | 1 | 1 |
Chlamydia trachomatis | phospholipase D superfamily protein | 0.0641 | 0 | 0.5 |
Brugia malayi | Phospholipase D. Active site motif family protein | 0.1395 | 0.2246 | 0.2246 |
Trypanosoma brucei | cardiolipin synthetase | 0.1395 | 0.2246 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.336 | 0.8094 | 1 |
Trypanosoma cruzi | cardiolipin synthetase, putative | 0.1395 | 0.2246 | 0.5 |
Echinococcus multilocularis | phospholipase D | 0.3534 | 0.8611 | 0.8562 |
Echinococcus granulosus | phospholipase D1 | 0.4001 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.336 | 0.8094 | 1 |
Entamoeba histolytica | phospholipase D, putative | 0.4001 | 1 | 1 |
Trypanosoma brucei | cardiolipin synthetase, putative | 0.1395 | 0.2246 | 1 |
Plasmodium falciparum | phosphatidylglycerophosphate synthase | 0.0641 | 0 | 0.5 |
Trypanosoma cruzi | cardiolipin synthetase, putative | 0.1395 | 0.2246 | 0.5 |
Plasmodium vivax | cardiolipin synthetase, putative | 0.0641 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | cardiolipin synthase | 0.0641 | 0 | 0.5 |
Echinococcus granulosus | phospholipase D | 0.3534 | 0.8611 | 0.8562 |
Toxoplasma gondii | phospholipase D active site domain-containing protein | 0.1395 | 0.2246 | 0.5 |
Chlamydia trachomatis | phospholipase D superfamily protein | 0.0641 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0755 | 0.034 | 0.042 |
Chlamydia trachomatis | phospholipase D endonuclease family protein | 0.0641 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2606 | 0.5848 | 0.7225 |
Chlamydia trachomatis | phospholipase D endonuclease family protein | 0.0641 | 0 | 0.5 |
Leishmania major | phosphatidylglycerophosphate synthase, putative | 0.0755 | 0.034 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.