Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glycogen phosphorylase | 0.1529 | 1 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1529 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1529 | 1 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1529 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.1025 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1056 | 0.1056 |
Echinococcus granulosus | glycogen phosphorylase | 0.1529 | 1 | 1 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0661 | 0.4306 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1529 | 1 | 1 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0661 | 0.4306 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.1529 | 1 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.1529 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.1529 | 1 | 1 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.1529 | 1 | 1 |
Chlamydia trachomatis | glycogen phosphorylase | 0.1529 | 1 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1529 | 1 | 1 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.1529 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0661 | 0.4306 | 0.4306 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1529 | 1 | 1 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.1529 | 1 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.1529 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.