Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | cyclin D, putative | 0.0114 | 0.2565 | 0.078 |
Plasmodium falciparum | protein kinase 5 | 0.014 | 0.4994 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.014 | 0.4994 | 0.3267 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.014 | 0.4994 | 0.3267 |
Brugia malayi | cell division control protein 2 homolog | 0.014 | 0.4994 | 0.3267 |
Trichomonas vaginalis | cyclin B3, putative | 0.0114 | 0.2565 | 0.078 |
Trichomonas vaginalis | cyclins, putative | 0.0193 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.014 | 0.4994 | 0.3267 |
Trichomonas vaginalis | cyclins, putative | 0.0193 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0114 | 0.2565 | 0.078 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.014 | 0.4994 | 0.3267 |
Giardia lamblia | Kinase, CMGC CDK | 0.014 | 0.4994 | 0.3267 |
Trichomonas vaginalis | cyclin D, putative | 0.0114 | 0.2565 | 0.078 |
Schistosoma mansoni | serine/threonine protein kinase | 0.014 | 0.4994 | 0.3267 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.014 | 0.4994 | 0.3267 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 1 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.014 | 0.4994 | 0.3267 |
Trichomonas vaginalis | cyclin B, putative | 0.0193 | 1 | 1 |
Plasmodium vivax | protein kinase Crk2 | 0.014 | 0.4994 | 0.5 |
Leishmania major | cyclin | 0.0193 | 1 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.014 | 0.4994 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0114 | 0.2565 | 0.078 |
Trypanosoma cruzi | cyclin, putative | 0.0193 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.4718 | 0.2896 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0193 | 1 | 1 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0193 | 1 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.014 | 0.4994 | 0.3267 |
Trypanosoma cruzi | cyclin, putative | 0.0193 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.014 | 0.4994 | 0.3793 |
Trichomonas vaginalis | cyclin B, putative | 0.0193 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0193 | 1 | 1 |
Echinococcus granulosus | cyclin B | 0.0193 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.014 | 0.4994 | 0.3267 |
Trichomonas vaginalis | cyclins, putative | 0.0193 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.014 | 0.4994 | 0.3267 |
Trichomonas vaginalis | CMGC family protein kinase | 0.014 | 0.4994 | 0.3793 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.014 | 0.4994 | 0.3267 |
Echinococcus granulosus | cyclin dependent kinase | 0.014 | 0.4994 | 0.3267 |
Trichomonas vaginalis | cyclin B, putative | 0.0114 | 0.2565 | 0.078 |
Schistosoma mansoni | cyclin B | 0.0193 | 1 | 1 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.014 | 0.4994 | 0.3267 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0193 | 1 | 1 |
Entamoeba histolytica | cyclin, putative | 0.0193 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.014 | 0.4994 | 0.3793 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0193 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase | 0.014 | 0.4994 | 0.3267 |
Trichomonas vaginalis | cyclin A, putative | 0.0193 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.014 | 0.4994 | 0.3267 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.014 | 0.4994 | 0.3267 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.014 | 0.4994 | 0.3267 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0193 | 1 | 1 |
Trypanosoma cruzi | cyclin 6, putative | 0.0193 | 1 | 1 |
Echinococcus multilocularis | cyclin B | 0.0193 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0193 | 1 | 1 |
Onchocerca volvulus | 0.0193 | 1 | 0.5 | |
Trichomonas vaginalis | cyclin B, putative | 0.0193 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.