Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Kinesin motor domain containing protein | 0.0055 | 0.0683 | 0.1492 |
Echinococcus multilocularis | kinesin family 1 | 0.0424 | 1 | 1 |
Onchocerca volvulus | 0.0231 | 0.5128 | 1 | |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0027 | 0.0027 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0419 | 0.0456 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0419 | 0.0419 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0419 | 0.0891 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.442 | 1 |
Loa Loa (eye worm) | kinesin-like protein KLP2 | 0.0055 | 0.0683 | 0.1492 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0419 | 0.0419 |
Plasmodium vivax | kinesin-5 | 0.0055 | 0.0683 | 1 |
Toxoplasma gondii | kinesin motor domain-containing protein | 0.0055 | 0.0683 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0419 | 0.0456 |
Schistosoma mansoni | kinesin eg-5 | 0.0055 | 0.0683 | 0.0764 |
Plasmodium falciparum | kinesin-5 | 0.0055 | 0.0683 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0419 | 0.0393 |
Entamoeba histolytica | kinesin, putative | 0.0055 | 0.0683 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0419 | 0.0891 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0419 | 0.0393 |
Giardia lamblia | Kinesin-5 | 0.0055 | 0.0683 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0369 | 0.8609 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0419 | 0.0456 |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.442 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0231 | 0.5128 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.