Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glycogen phosphorylase | 0.0318 | 0.3477 | 0.3452 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0144 | 0.071 | 0.0675 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0318 | 0.3477 | 0.3452 |
Schistosoma mansoni | hypothetical protein | 0.0137 | 0.0591 | 0.0555 |
Echinococcus granulosus | glycogen phosphorylase | 0.0318 | 0.3477 | 0.3452 |
Brugia malayi | carbohydrate phosphorylase | 0.0318 | 0.3477 | 0.3452 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0144 | 0.071 | 0.0675 |
Giardia lamblia | Glycogen phosphorylase | 0.0318 | 0.3477 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0318 | 0.3477 | 0.3452 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0102 | 0.0038 | 0.0109 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0144 | 0.071 | 0.0675 |
Echinococcus granulosus | glycogen phosphorylase | 0.0318 | 0.3477 | 0.3452 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0318 | 0.3477 | 0.3452 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0138 | 0.0609 | 0.5 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0099 | 0 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0138 | 0.0609 | 0.175 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0144 | 0.071 | 0.0675 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0144 | 0.071 | 0.0675 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0729 | 1 | 1 |
Trichomonas vaginalis | rotamase, putative | 0.0102 | 0.0038 | 0.0109 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0318 | 0.3477 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0138 | 0.0609 | 0.0573 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0144 | 0.071 | 0.0675 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.0138 | 0.0609 | 0.175 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0729 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0318 | 0.3477 | 0.3452 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0138 | 0.0609 | 0.175 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0144 | 0.071 | 0.0675 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0729 | 1 | 1 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0318 | 0.3477 | 0.3452 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0099 | 0 | 0.5 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0138 | 0.0609 | 0.5 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0729 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0318 | 0.3477 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0318 | 0.3477 | 1 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0318 | 0.3477 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0318 | 0.3477 | 1 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0099 | 0 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0318 | 0.3477 | 0.5 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0099 | 0 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0318 | 0.3477 | 0.3452 |
Trypanosoma brucei | RNA helicase, putative | 0.0137 | 0.0591 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.