Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.016 | 0.6384 | 1 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0106 | 0 | 0.5 |
Schistosoma mansoni | glutamate receptor NMDA | 0.016 | 0.6384 | 0.6384 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0113 | 0.0881 | 0.1379 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0106 | 0 | 0.5 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0113 | 0.0881 | 0.1379 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0106 | 0 | 0.5 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0106 | 0 | 0.5 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0117 | 0.1323 | 0.2072 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0113 | 0.0881 | 0.1379 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0113 | 0.0881 | 0.1379 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.016 | 0.6384 | 1 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0117 | 0.1323 | 0.0803 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0113 | 0.0881 | 0.1379 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.