Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | histone deacetylase 4 | 0.1735 | 0.1326 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1735 | 0.1326 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1512 | 0.0889 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.6163 | 1 | 1 |
Plasmodium vivax | histone deacetylase 2, putative | 0.1735 | 0.1326 | 1 |
Plasmodium vivax | histone deacetylase, putative | 0.1735 | 0.1326 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.1512 | 0.0889 | 0.0889 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.1735 | 0.1326 | 0.048 |
Echinococcus granulosus | histone deacetylase 6 | 0.1787 | 0.1429 | 0.0593 |
Echinococcus multilocularis | acetylcholinesterase | 0.6163 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1512 | 0.0889 | 0.0889 |
Loa Loa (eye worm) | hypothetical protein | 0.1111 | 0.0103 | 0.0103 |
Brugia malayi | Histone deacetylase family protein | 0.1735 | 0.1326 | 0.048 |
Trypanosoma brucei | histone deacetylase, putative | 0.1735 | 0.1326 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1787 | 0.1429 | 0.0593 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1512 | 0.0889 | 0.5 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1735 | 0.1326 | 0.048 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.1735 | 0.1326 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1512 | 0.0889 | 0.5 |
Echinococcus granulosus | histone deacetylase | 0.1735 | 0.1326 | 0.048 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.6163 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1512 | 0.0889 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.6163 | 1 | 1 |
Leishmania major | histone deacetylase, putative | 0.1735 | 0.1326 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.6163 | 1 | 1 |
Schistosoma mansoni | histone deacetylase hda2 | 0.1787 | 0.1429 | 0.0593 |
Loa Loa (eye worm) | hypothetical protein | 0.6163 | 1 | 1 |
Plasmodium falciparum | histone deacetylase 2 | 0.1735 | 0.1326 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1735 | 0.1326 | 1 |
Trypanosoma brucei | histone deacetylase 3 | 0.1735 | 0.1326 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1512 | 0.0889 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1512 | 0.0889 | 0.5 |
Loa Loa (eye worm) | histone deacetylase | 0.1735 | 0.1326 | 0.1326 |
Echinococcus multilocularis | histone deacetylase | 0.1735 | 0.1326 | 0.048 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.1512 | 0.0889 | 0.0889 |
Plasmodium falciparum | histone deacetylase, putative | 0.1735 | 0.1326 | 1 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.1735 | 0.1326 | 0.1326 |
Giardia lamblia | Histone deacetylase | 0.1512 | 0.0889 | 0.5 |
Echinococcus granulosus | histone deacetylase 6 | 0.1735 | 0.1326 | 0.048 |
Entamoeba histolytica | histone deacetylase, putative | 0.1512 | 0.0889 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1512 | 0.0889 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.6163 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1735 | 0.1326 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1512 | 0.0889 | 0.5 |
Echinococcus granulosus | histone deacetylase 6 | 0.1735 | 0.1326 | 0.048 |
Brugia malayi | Histone deacetylase family protein | 0.1735 | 0.1326 | 0.048 |
Loa Loa (eye worm) | carboxylesterase | 0.6163 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1512 | 0.0889 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.1735 | 0.1326 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.6163 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 7 | 0.1735 | 0.1326 | 0.048 |
Echinococcus granulosus | acetylcholinesterase | 0.6163 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.6163 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.6163 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1735 | 0.1326 | 0.048 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.1735 | 0.1326 | 0.048 |
Echinococcus granulosus | histone deacetylase 7 | 0.1735 | 0.1326 | 0.048 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.