Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | histone deacetylase, putative | 0.009 | 0 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0107 | 0.0415 | 1 |
Loa Loa (eye worm) | tyrosinase 1 | 0.0107 | 0.0415 | 1 |
Echinococcus multilocularis | geminin | 0.0197 | 0.2566 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.2566 | 0.2566 |
Trypanosoma brucei | histone deacetylase 4 | 0.009 | 0 | 0.5 |
Plasmodium falciparum | histone deacetylase, putative | 0.009 | 0 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.009 | 0 | 0.5 |
Trypanosoma brucei | histone deacetylase, putative | 0.009 | 0 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.009 | 0 | 0.5 |
Schistosoma mansoni | tyrosinase precursor | 0.0509 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0415 | 1 |
Echinococcus granulosus | geminin | 0.0197 | 0.2566 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0107 | 0.0415 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.2566 | 0.2566 |
Onchocerca volvulus | 0.0107 | 0.0415 | 0.5 | |
Trypanosoma cruzi | histone deacetylase, putative | 0.009 | 0 | 0.5 |
Onchocerca volvulus | 0.0107 | 0.0415 | 0.5 | |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0107 | 0.0415 | 1 |
Onchocerca volvulus | 0.0107 | 0.0415 | 0.5 | |
Onchocerca volvulus | 0.0107 | 0.0415 | 0.5 | |
Leishmania major | histone deacetylase, putative | 0.009 | 0 | 0.5 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0107 | 0.0415 | 1 |
Plasmodium vivax | histone deacetylase 2, putative | 0.009 | 0 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.009 | 0 | 0.5 |
Brugia malayi | Common central domain of tyrosinase family protein | 0.0107 | 0.0415 | 1 |
Plasmodium falciparum | histone deacetylase 2 | 0.009 | 0 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.0107 | 0.0415 | 1 |
Trypanosoma brucei | histone deacetylase 3 | 0.009 | 0 | 0.5 |
Brugia malayi | ShTK domain containing protein | 0.0107 | 0.0415 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0415 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.009 | 0 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0107 | 0.0415 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.