Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0691 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0691 | 1 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0148 | 0.162 | 0.162 |
Trypanosoma brucei | histone deacetylase, putative | 0.0282 | 0.3685 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.0227 | 0.2836 | 0.2836 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0282 | 0.3685 | 0.3685 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0288 | 0.3778 | 0.3778 |
Echinococcus granulosus | histone deacetylase | 0.0282 | 0.3685 | 0.3685 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0691 | 1 | 1 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0227 | 0.2836 | 0.5 |
Plasmodium vivax | histone deacetylase, putative | 0.0282 | 0.3685 | 0.1184 |
Echinococcus granulosus | histone deacetylase 1 | 0.0691 | 1 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0282 | 0.3685 | 0.3685 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0282 | 0.3685 | 0.1184 |
Plasmodium falciparum | histone deacetylase 1 | 0.0691 | 1 | 1 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0282 | 0.3685 | 0.3685 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0148 | 0.162 | 0.162 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0691 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0161 | 0.183 | 0.183 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0282 | 0.3685 | 0.1184 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0691 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0227 | 0.2836 | 0.2836 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0691 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0188 | 0.0188 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0691 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0288 | 0.3778 | 0.3778 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0691 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0282 | 0.3685 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1319 | 0.1319 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0148 | 0.162 | 0.162 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0227 | 0.2836 | 0.2836 |
Loa Loa (eye worm) | hypothetical protein | 0.0691 | 1 | 1 |
Giardia lamblia | Histone deacetylase | 0.0691 | 1 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0691 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0691 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0691 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0691 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0282 | 0.3685 | 0.3685 |
Brugia malayi | histone deacetylase 11 | 0.0227 | 0.2836 | 0.2836 |
Trypanosoma brucei | histone deacetylase 3 | 0.0282 | 0.3685 | 0.1184 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0691 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 7 | 0.0282 | 0.3685 | 0.3685 |
Schistosoma mansoni | histone deacetylase | 0.0691 | 1 | 1 |
Trypanosoma brucei | histone deacetylase 4 | 0.0282 | 0.3685 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.028 | 0.028 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0282 | 0.3685 | 0.3685 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0282 | 0.3685 | 0.3685 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0227 | 0.2836 | 0.2836 |
Leishmania major | histone deacetylase, putative | 0.0691 | 1 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0691 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0161 | 0.183 | 0.183 |
Echinococcus granulosus | histone deacetylase 8 | 0.0227 | 0.2836 | 0.2836 |
Brugia malayi | Histone deacetylase 1 | 0.0691 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0691 | 1 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0282 | 0.3685 | 0.3685 |
Trypanosoma brucei | histone deacetylase 1 | 0.0691 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0691 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0282 | 0.3685 | 0.3685 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0691 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0282 | 0.3685 | 0.1184 |
Echinococcus granulosus | histone deacetylase 6 | 0.0282 | 0.3685 | 0.3685 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0148 | 0.162 | 0.162 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0691 | 1 | 1 |
Entamoeba histolytica | histone deacetylase, putative | 0.0691 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0282 | 0.3685 | 0.1184 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0691 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0691 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0691 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 3 | 0.0691 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase | 0.0282 | 0.3685 | 0.3685 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0227 | 0.2836 | 0.2836 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0288 | 0.3778 | 0.3778 |
Loa Loa (eye worm) | histone deacetylase | 0.0282 | 0.3685 | 0.3685 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0282 | 0.3685 | 0.3685 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.