Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hexokinase 1 | 0.0157 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0157 | 1 | 1 |
Echinococcus granulosus | hexokinase type 2 | 0.0157 | 1 | 1 |
Schistosoma mansoni | hexokinase | 0.0157 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.0157 | 1 | 1 |
Leishmania major | hexokinase, putative | 0.0157 | 1 | 0.5 |
Entamoeba histolytica | hexokinase 2 | 0.0157 | 1 | 0.5 |
Onchocerca volvulus | 0.0157 | 1 | 1 | |
Loa Loa (eye worm) | hexokinase | 0.0157 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.3085 | 0.3085 |
Echinococcus granulosus | hexokinase | 0.0157 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.0157 | 1 | 1 |
Loa Loa (eye worm) | galactoside-binding lectin family protein | 0.0122 | 0.3085 | 0.3085 |
Trypanosoma brucei | hexokinase | 0.0157 | 1 | 0.5 |
Onchocerca volvulus | 0.0157 | 1 | 1 | |
Leishmania major | hexokinase, putative | 0.0157 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.0157 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.3085 | 0.3085 |
Echinococcus multilocularis | hexokinase type 2 | 0.0157 | 1 | 1 |
Echinococcus granulosus | hexokinase | 0.0157 | 1 | 1 |
Trypanosoma brucei | hexokinase, putative | 0.0157 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0157 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.3085 | 0.3085 |
Plasmodium falciparum | hexokinase | 0.0157 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase type II | 0.0157 | 1 | 1 |
Loa Loa (eye worm) | galectin | 0.0122 | 0.3085 | 0.3085 |
Trypanosoma cruzi | hexokinase, putative | 0.0157 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.0157 | 1 | 0.5 |
Treponema pallidum | hexokinase (hxk) | 0.0157 | 1 | 0.5 |
Loa Loa (eye worm) | galactoside-binding lectin family protein | 0.0122 | 0.3085 | 0.3085 |
Echinococcus multilocularis | hexokinase | 0.0157 | 1 | 1 |
Plasmodium vivax | hexokinase, putative | 0.0157 | 1 | 0.5 |
Onchocerca volvulus | 0.0157 | 1 | 1 | |
Toxoplasma gondii | hexokinase | 0.0157 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0157 | 1 | 1 |
Loa Loa (eye worm) | galectin | 0.0122 | 0.3085 | 0.3085 |
Loa Loa (eye worm) | galactoside-binding lectin family protein | 0.0122 | 0.3085 | 0.3085 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.