Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | caspase-7 (C14 family) | 0.0662 | 0.2673 | 0.2673 |
Schistosoma mansoni | inhibitor of apoptosis protein | 0.2172 | 1 | 1 |
Brugia malayi | Cell death protein 3 precursor | 0.0662 | 0.2673 | 0.2673 |
Brugia malayi | gamma-secretase subunit aph-1 | 0.0243 | 0.0641 | 0.0641 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0662 | 0.2673 | 0.2172 |
Echinococcus multilocularis | inhibitor of apoptosis protein | 0.2172 | 1 | 1 |
Onchocerca volvulus | Deterin homolog | 0.2172 | 1 | 1 |
Schistosoma mansoni | gamma-secretase subunit aph-1 | 0.0243 | 0.0641 | 0.0641 |
Loa Loa (eye worm) | hypothetical protein | 0.2172 | 1 | 1 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0662 | 0.2673 | 0.2172 |
Brugia malayi | hypothetical protein | 0.0662 | 0.2673 | 0.2673 |
Loa Loa (eye worm) | hypothetical protein | 0.0662 | 0.2673 | 0.2673 |
Schistosoma mansoni | hypothetical protein | 0.2172 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0662 | 0.2673 | 0.2673 |
Onchocerca volvulus | 0.2172 | 1 | 1 | |
Loa Loa (eye worm) | gamma-secretase subunit aph-1 | 0.0243 | 0.0641 | 0.0641 |
Schistosoma mansoni | hypothetical protein | 0.0662 | 0.2673 | 0.2673 |
Onchocerca volvulus | 0.0662 | 0.2673 | 0.2673 | |
Loa Loa (eye worm) | hypothetical protein | 0.2172 | 1 | 1 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0662 | 0.2673 | 0.2673 |
Echinococcus multilocularis | caspase 2 | 0.0662 | 0.2673 | 0.2172 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.2172 | 1 | 1 |
Echinococcus granulosus | baculoviral IAP repeat containing protein | 0.2172 | 1 | 1 |
Echinococcus granulosus | caspase 2 | 0.0662 | 0.2673 | 0.2172 |
Schistosoma mansoni | inhibitor of apoptosis (iap) domain family member | 0.2172 | 1 | 1 |
Echinococcus multilocularis | baculoviral IAP repeat containing protein | 0.2172 | 1 | 1 |
Echinococcus granulosus | inhibitor of apoptosis protein | 0.2172 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.