Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.131 | 0.3111 | 0.0416 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.131 | 0.3111 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.1492 | 0.3921 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.131 | 0.3111 | 0.0051 |
Onchocerca volvulus | Arrow homolog | 0.1302 | 0.3076 | 0.4813 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.2862 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1492 | 0.3921 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.1492 | 0.3921 | 1 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.1302 | 0.3076 | 1 |
Brugia malayi | Trypsin family protein | 0.1492 | 0.3921 | 1 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.1302 | 0.3076 | 1 |
Onchocerca volvulus | 0.1492 | 0.3921 | 1 | |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.1492 | 0.3921 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.