Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | fibrillin 1 | 0.0828 | 0.5249 | 0.5 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0828 | 0.5249 | 1 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0828 | 0.5249 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.1044 | 1 | 1 |
Echinococcus multilocularis | laminin | 0.0828 | 0.5249 | 0.5 |
Echinococcus granulosus | Tolloid protein 1 | 0.0828 | 0.5249 | 0.5 |
Onchocerca volvulus | Arrow homolog | 0.0828 | 0.5249 | 0.0729 |
Loa Loa (eye worm) | hypothetical protein | 0.1044 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1044 | 1 | 1 |
Onchocerca volvulus | 0.1044 | 1 | 1 | |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0828 | 0.5249 | 1 |
Echinococcus granulosus | laminin | 0.0828 | 0.5249 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.1044 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.