Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | peptide deformylase, putative | 0.1451 | 1 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0553 | 0 | 0.5 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.0553 | 0 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0553 | 0 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0553 | 0 | 0.5 |
Plasmodium falciparum | peptide deformylase | 0.1451 | 1 | 0.5 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.0553 | 0 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0553 | 0 | 0.5 |
Trypanosoma brucei | Peptide deformylase 2 | 0.0553 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.1451 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.1451 | 1 | 0.5 |
Treponema pallidum | polypeptide deformylase (def) | 0.1451 | 1 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.1451 | 1 | 0.5 |
Mycobacterium ulcerans | peptide deformylase | 0.1451 | 1 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.1451 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.