Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | jun protein | 0.0082 | 1 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0068 | 0.096 | 0.5 |
Echinococcus multilocularis | jun protein | 0.0082 | 1 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0068 | 0.096 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0068 | 0.096 | 0.5 |
Schistosoma mansoni | jun-related protein | 0.0066 | 0 | 0.5 |
Mycobacterium ulcerans | lysophospholipase | 0.0068 | 0.096 | 0.5 |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.0068 | 0.096 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0068 | 0.096 | 0.5 |
Plasmodium falciparum | esterase, putative | 0.0068 | 0.096 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0068 | 0.096 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0 | 0.5 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0068 | 0.096 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0068 | 0.096 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0068 | 0.096 | 0.5 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.0068 | 0.096 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.8537 | 0.5 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0068 | 0.096 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0068 | 0.096 | 0.5 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.0068 | 0.096 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0068 | 0.096 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0068 | 0.096 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0068 | 0.096 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0082 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0068 | 0.096 | 0.5 |
Plasmodium vivax | PST-A protein | 0.0068 | 0.096 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0068 | 0.096 | 0.5 |
Mycobacterium tuberculosis | Possible lysophospholipase | 0.0068 | 0.096 | 0.5 |
Leishmania major | monoglyceride lipase, putative | 0.0068 | 0.096 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0082 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.