Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | peptide deformylase | 0.0507 | 1 | 0.5 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.0193 | 0 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0193 | 0 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0193 | 0 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0193 | 0 | 0.5 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.0193 | 0 | 0.5 |
Plasmodium vivax | peptide deformylase, putative | 0.0507 | 1 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0507 | 1 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.0507 | 1 | 0.5 |
Mycobacterium ulcerans | peptide deformylase | 0.0507 | 1 | 0.5 |
Treponema pallidum | polypeptide deformylase (def) | 0.0507 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.0507 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.0507 | 1 | 0.5 |
Trypanosoma brucei | Peptide deformylase 2 | 0.0193 | 0 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0193 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.