TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 330.378 | Formula: C18H22N2O4
H donors: 0 H acceptors: 2 LogP: 2.87 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: C=COC(=O)N1CCC(CC1)N1[C@@H](COC1=O)Cc1ccccc1
InChi: 1S/C18H22N2O4/c1-2-23-17(21)19-10-8-15(9-11-19)20-16(13-24-18(20)22)12-14-6-4-3-5-7-14/h2-7,15-16H,1,8-13H2/t16-/m0/s1
InChiKey: DIZCVMGZLQFLHY-INIZCTEOSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0082	0.1233	0.1162
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0145	0.2597	0.2537
Schistosoma mansoni	ceramide glucosyltransferase	0.0487	1	1
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0145	0.2597	0.2597
Schistosoma mansoni	amine GPCR	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0145	0.2597	0.2597
Echinococcus granulosus	neuropeptide Y receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	neuropeptides capa receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	biogenic amine 5HT receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	orexin receptor type 2	0.0145	0.2597	0.2537
Brugia malayi	Melatonin receptor type 1A	0.0145	0.2597	0.2597
Echinococcus multilocularis	g protein coupled receptor	0.0145	0.2597	0.2537
Trypanosoma cruzi	Peptide deformylase 2, putative	0.0087	0.1336	1
Brugia malayi	follicle stimulating hormone receptor	0.0145	0.2597	0.2597
Plasmodium vivax	peptide deformylase, putative	0.0227	0.4382	0.5
Loa Loa (eye worm)	kelch domain-containing protein family protein	0.0055	0.0652	0.0652
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0652	0.0652
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Schistosoma mansoni	hypothetical protein	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus multilocularis	fmrfamide receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	neuropeptide F receptor	0.0145	0.2597	0.2597
Brugia malayi	Serotonin receptor	0.0145	0.2597	0.2597
Echinococcus granulosus	neuropeptide Y receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	opsin-like receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	neuropeptide f receptor 76f	0.0145	0.2597	0.2537
Schistosoma mansoni	voltage-gated potassium channel	0.009	0.1396	0.1326
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0145	0.2597	0.2537
Leishmania major	polypeptide deformylase-like protein, putative	0.0087	0.1336	1
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Trypanosoma brucei	Polypeptide deformylase 1	0.0087	0.1336	1
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0145	0.2597	0.2537
Brugia malayi	RE15519p	0.0145	0.2597	0.2597
Echinococcus granulosus	g-protein coupled receptor	0.0145	0.2597	0.2537
Brugia malayi	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	orexin receptor type 2	0.0145	0.2597	0.2537
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0145	0.2597	0.2537
Brugia malayi	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Schistosoma mansoni	hypothetical protein	0.0145	0.2597	0.2537
Brugia malayi	Serotonin receptor	0.0145	0.2597	0.2597
Brugia malayi	Dopamine receptor	0.0145	0.2597	0.2597
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0145	0.2597	0.2597
Echinococcus multilocularis	sex peptide receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.2597	0.2537
Echinococcus granulosus	tm gpcr rhodopsin	0.0145	0.2597	0.2537
Schistosoma mansoni	voltage-gated potassium channel	0.009	0.1396	0.1326
Echinococcus multilocularis	ceramide glucosyltransferase	0.0487	1	1
Onchocerca volvulus	Ceramide glucosyltransferase homolog	0.0487	1	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.2597	0.2537
Echinococcus granulosus	serotonin receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	g protein coupled receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0145	0.2597	0.2537
Echinococcus multilocularis	nmda type glutamate receptor	0.0032	0.0149	0.0068
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0145	0.2597	0.2537
Trypanosoma brucei	Peptide deformylase 2	0.0087	0.1336	1
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0145	0.2597	0.2537
Echinococcus granulosus	neuropeptide receptor A26	0.0145	0.2597	0.2537
Echinococcus granulosus	dro:myosuppressin receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	neuropeptide receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Mycobacterium leprae	PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE)	0.0227	0.4382	0.5
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Trypanosoma cruzi	polypeptide deformylase-like protein, putative	0.0087	0.1336	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.2597	0.2537
Echinococcus multilocularis	neuropeptide s receptor	0.0145	0.2597	0.2537
Brugia malayi	hypothetical protein	0.0145	0.2597	0.2597
Brugia malayi	hypothetical protein	0.0145	0.2597	0.2597
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.2597	0.2537
Echinococcus multilocularis	neuropeptide Y receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	dro:myosuppressin receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Schistosoma mansoni	neuropeptide receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0145	0.2597	0.2537
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0145	0.2597	0.2537
Schistosoma mansoni	growth hormone secretagogue receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	opsin-like receptor	0.0145	0.2597	0.2537
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0077	0.1116	0.5
Brugia malayi	larval opioid receptor	0.0145	0.2597	0.2597
Brugia malayi	G protein-coupled receptor	0.0145	0.2597	0.2597
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	TYRA-2 protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	neuropeptide F receptor	0.0145	0.2597	0.2597
Schistosoma mansoni	neuropeptide receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Schistosoma mansoni	histamine h1 receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	neuropeptide FF receptor 2	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Trypanosoma cruzi	Peptide deformylase 2, putative	0.0087	0.1336	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.2597	0.2537
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Brugia malayi	hypothetical protein	0.0145	0.2597	0.2597
Brugia malayi	putative neuropeptide receptor	0.0145	0.2597	0.2597
Brugia malayi	hypothetical protein	0.0055	0.0652	0.0652
Loa Loa (eye worm)	hypothetical protein	0.0071	0.0999	0.0999
Schistosoma mansoni	amine GPCR	0.0145	0.2597	0.2537
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0145	0.2597	0.2537
Schistosoma mansoni	opsin-like receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0145	0.2597	0.2537
Brugia malayi	ORL1-like opioid receptor	0.0145	0.2597	0.2597
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Brugia malayi	G-protein coupled receptor	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	neuropeptide receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	amine GPCR	0.0145	0.2597	0.2537
Brugia malayi	putative neuropeptide receptor NPR1	0.0145	0.2597	0.2597
Echinococcus granulosus	fmrfamide receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Mycobacterium tuberculosis	Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase)	0.0227	0.4382	0.5
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	neuropeptide Y receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	biogenic amine receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Brugia malayi	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0145	0.2597	0.2537
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	hypothetical protein	0.0145	0.2597	0.2537
Brugia malayi	neuropeptide F receptor	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.2597	0.2537
Brugia malayi	Integrin beta pat-3 precursor	0.0351	0.707	0.707
Schistosoma mansoni	hypothetical protein	0.0145	0.2597	0.2537
Trypanosoma cruzi	polypeptide deformylase-like protein, putative	0.0087	0.1336	1
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0145	0.2597	0.2597
Echinococcus multilocularis	allatostatin A receptor	0.0145	0.2597	0.2537
Brugia malayi	Dopamine receptor protein 2	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0145	0.2597	0.2537
Brugia malayi	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0145	0.2597	0.2537
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0082	0.1233	0.1233
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	G-protein coupled receptor	0.0145	0.2597	0.2597
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0145	0.2597	0.2537
Brugia malayi	G-protein coupled receptor	0.0145	0.2597	0.2597
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0077	0.1116	0.5
Schistosoma mansoni	adenoreceptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	integrin beta 2	0.0257	0.503	0.499
Giardia lamblia	Ceramide glucosyltransferase	0.0221	0.4236	0.5
Echinococcus granulosus	allatostatin A receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Brugia malayi	AKH receptor	0.0145	0.2597	0.2597
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0145	0.2597	0.2597
Echinococcus multilocularis	Glutamate receptor, ionotropic kainate 3	0.0032	0.0149	0.0068
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0145	0.2597	0.2537
Loa Loa (eye worm)	ceramide glucosyltransferase	0.0487	1	1
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	7TM GPCR rhodopsin	0.0145	0.2597	0.2537
Schistosoma mansoni	amine GPCR	0.0145	0.2597	0.2537
Schistosoma mansoni	biogenic amine receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	G protein coupled receptor 139	0.0145	0.2597	0.2537
Echinococcus granulosus	neuropeptides capa receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Toxoplasma gondii	hypothetical protein	0.0227	0.4382	0.5
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Schistosoma mansoni	neuropeptide receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	ceramide glucosyltransferase	0.0487	1	1
Echinococcus multilocularis	g protein coupled receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	serotonin receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	somatostatin receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0082	0.1233	0.1162
Echinococcus multilocularis	neuropeptide receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.2597	0.2537
Schistosoma mansoni	amine GPCR	0.0145	0.2597	0.2537
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus multilocularis	somatostatin receptor	0.0145	0.2597	0.2537
Chlamydia trachomatis	peptide deformylase	0.0227	0.4382	0.5
Brugia malayi	Dopamine receptor protein 1	0.0145	0.2597	0.2597
Echinococcus multilocularis	g-protein coupled receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	myosin xvIII	0.0145	0.2597	0.2537
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	integrin beta-2	0.0351	0.707	0.707
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	melatonin receptor type 1A	0.0145	0.2597	0.2597
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.2597	0.2537
Echinococcus granulosus	sex peptide receptor	0.0145	0.2597	0.2537
Wolbachia endosymbiont of Brugia malayi	peptide deformylase	0.0227	0.4382	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.2597	0.2537
Echinococcus multilocularis	serotonin receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	g protein coupled receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus multilocularis	neuropeptides capa receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	neuropeptide receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	neuropeptide s receptor	0.0145	0.2597	0.2537
Plasmodium falciparum	peptide deformylase	0.0227	0.4382	0.5
Loa Loa (eye worm)	G-protein coupled receptor	0.0145	0.2597	0.2597
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0082	0.1233	0.1233
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus multilocularis	neuropeptide receptor A26	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Brugia malayi	sulfakinin receptor protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0145	0.2597	0.2597
Treponema pallidum	polypeptide deformylase (def)	0.0227	0.4382	0.5
Brugia malayi	G protein-coupled receptor F59B2.13	0.0145	0.2597	0.2597
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0145	0.2597	0.2537
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0145	0.2597	0.2597
Schistosoma mansoni	neuropeptide F-like receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	g protein coupled receptor	0.0145	0.2597	0.2537
Echinococcus multilocularis	neuropeptides capa receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	biogenic amine 5HT receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	7tm_1 domain containing protein	0.0145	0.2597	0.2537
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0145	0.2597	0.2597
Echinococcus multilocularis	neuropeptide receptor	0.0145	0.2597	0.2537
Brugia malayi	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus multilocularis	fmrfamide receptor	0.0145	0.2597	0.2537
Brugia malayi	Kelch motif family protein	0.0055	0.0652	0.0652
Schistosoma mansoni	integrin beta subunit	0.0202	0.3835	0.3785
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	g protein coupled receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	ceramide glucosyltransferase	0.0487	1	1
Echinococcus granulosus	nmda type glutamate receptor	0.0032	0.0149	0.0068
Mycobacterium ulcerans	peptide deformylase	0.0227	0.4382	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0145	0.2597	0.2537
Echinococcus multilocularis	integrin beta 2	0.0257	0.503	0.499
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0145	0.2597	0.2597
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.2597	0.2537
Schistosoma mansoni	biogenic amine receptor	0.0145	0.2597	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	tm gpcr rhodopsin	0.0145	0.2597	0.2537
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0145	0.2597	0.2537
Brugia malayi	neuropeptide F receptor	0.0145	0.2597	0.2597
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	neuropeptide F-like receptor	0.0145	0.2597	0.2537
Echinococcus granulosus	G protein coupled receptor 139	0.0145	0.2597	0.2537
Brugia malayi	hypothetical protein	0.0145	0.2597	0.2597
Brugia malayi	GnHR receptor homolog	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0145	0.2597	0.2537
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0145	0.2597	0.2537
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0145	0.2597	0.2537
Schistosoma mansoni	hypothetical protein	0.0145	0.2597	0.2537
Brugia malayi	hypothetical protein	0.0145	0.2597	0.2597
Loa Loa (eye worm)	hypothetical protein	0.0145	0.2597	0.2597
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0145	0.2597	0.2537

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 884874