Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | aminopeptidase, putative | 0.0234 | 0.1324 | 0.5 |
Schistosoma mansoni | family M1 non-peptidase homologue (M01 family) | 0.0152 | 0.0051 | 0.0387 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0234 | 0.1324 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0234 | 0.1324 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0234 | 0.1324 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0234 | 0.1324 | 0.1324 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.0051 | 0.0059 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0234 | 0.1324 | 0.1324 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.0051 | 0.0059 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0234 | 0.1324 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0234 | 0.1324 | 0.1324 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0234 | 0.1324 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0234 | 0.1324 | 0.1324 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0234 | 0.1324 | 0.1324 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0643 | 0.7653 | 0.8769 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0234 | 0.1324 | 0.1324 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0234 | 0.1324 | 1 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0234 | 0.1324 | 0.5 |
Onchocerca volvulus | 0.0795 | 1 | 1 | |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0234 | 0.1324 | 0.1324 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0234 | 0.1324 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0152 | 0.0051 | 0.0051 |
Echinococcus multilocularis | aminopeptidase N | 0.0795 | 1 | 1 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0234 | 0.1324 | 0.5 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0234 | 0.1324 | 0.5 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0234 | 0.1324 | 1 |
Echinococcus granulosus | aminopeptidase N | 0.0795 | 1 | 1 |
Loa Loa (eye worm) | aminopeptidase N | 0.0234 | 0.1324 | 0.1517 |
Loa Loa (eye worm) | hypothetical protein | 0.0561 | 0.6381 | 0.7311 |
Loa Loa (eye worm) | hypothetical protein | 0.0712 | 0.8727 | 1 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0234 | 0.1324 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0234 | 0.1324 | 0.1324 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0234 | 0.1324 | 0.1324 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0234 | 0.1324 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0234 | 0.1324 | 0.1324 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.