Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Kinase, CMGC CDK | 0.0538 | 0.0402 | 1 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0538 | 0.0402 | 0.1613 |
Plasmodium falciparum | protein kinase 5 | 0.0538 | 0.0402 | 0.5 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.1101 | 0.249 | 0.249 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0538 | 0.0402 | 0.0402 |
Brugia malayi | cell division control protein 2 homolog | 0.0538 | 0.0402 | 0.1015 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0538 | 0.0402 | 0.1613 |
Brugia malayi | Protein kinase domain containing protein | 0.1101 | 0.249 | 0.6296 |
Brugia malayi | Protein kinase domain containing protein | 0.0538 | 0.0402 | 0.1015 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0538 | 0.0402 | 0.0402 |
Entamoeba histolytica | protein kinase, putative | 0.1101 | 0.249 | 1 |
Plasmodium vivax | protein kinase Crk2 | 0.0538 | 0.0402 | 0.5 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.1101 | 0.249 | 1 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.1101 | 0.249 | 1 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0538 | 0.0402 | 0.0402 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0538 | 0.0402 | 0.1613 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0538 | 0.0402 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3124 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1496 | 0.3956 | 0.3956 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.1101 | 0.249 | 1 |
Brugia malayi | hypothetical protein | 0.1496 | 0.3956 | 1 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0538 | 0.0402 | 0.1613 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1101 | 0.249 | 0.249 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0538 | 0.0402 | 0.0402 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0538 | 0.0402 | 0.1613 |
Loa Loa (eye worm) | hypothetical protein | 0.0521 | 0.0339 | 0.0339 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0538 | 0.0402 | 0.0402 |
Loa Loa (eye worm) | hypothetical protein | 0.1084 | 0.2428 | 0.2428 |
Giardia lamblia | Kinase, CMGC CDK | 0.0538 | 0.0402 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0538 | 0.0402 | 1 |
Echinococcus multilocularis | dual specificity | 0.1101 | 0.249 | 0.249 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0538 | 0.0402 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1084 | 0.2428 | 0.2428 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0538 | 0.0402 | 0.0402 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0538 | 0.0402 | 0.0402 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0538 | 0.0402 | 0.1613 |
Echinococcus granulosus | cyclin dependent kinase | 0.0538 | 0.0402 | 0.0402 |
Entamoeba histolytica | protein kinase domain containing protein | 0.1101 | 0.249 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0538 | 0.0402 | 0.0402 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0538 | 0.0402 | 0.1613 |
Entamoeba histolytica | hypothetical protein | 0.1101 | 0.249 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0538 | 0.0402 | 0.0402 |
Loa Loa (eye worm) | hypothetical protein | 0.1496 | 0.3956 | 0.3956 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0538 | 0.0402 | 0.1613 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0538 | 0.0402 | 0.0402 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0538 | 0.0402 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 5 activator 1 | 0.3124 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0538 | 0.0402 | 0.0402 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0538 | 0.0402 | 0.0402 |
Entamoeba histolytica | protein kinase, putative | 0.1101 | 0.249 | 1 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.1101 | 0.249 | 1 |
Schistosoma mansoni | cyclin-dependent kinase 5 activator | 0.3124 | 1 | 1 |
Echinococcus granulosus | dual specificity | 0.1101 | 0.249 | 0.249 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.