Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.1023 | 0.2573 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.05 | 0.0507 | 1 |
Echinococcus multilocularis | dual specificity | 0.1023 | 0.2573 | 0.2573 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.05 | 0.0507 | 0.0507 |
Entamoeba histolytica | protein kinase, putative | 0.1023 | 0.2573 | 1 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.05 | 0.0507 | 0.197 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.05 | 0.0507 | 0.0507 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.05 | 0.0507 | 0.197 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.05 | 0.0507 | 0.0507 |
Schistosoma mansoni | serine/threonine protein kinase | 0.05 | 0.0507 | 0.0507 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.05 | 0.0507 | 0.197 |
Plasmodium falciparum | protein kinase 5 | 0.05 | 0.0507 | 0.5 |
Echinococcus multilocularis | cyclin dependent kinase 5 activator 1 | 0.2903 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.1023 | 0.2573 | 0.6397 |
Loa Loa (eye worm) | hypothetical protein | 0.1007 | 0.2511 | 0.2511 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.05 | 0.0507 | 0.197 |
Entamoeba histolytica | protein kinase, putative | 0.1023 | 0.2573 | 1 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.05 | 0.0507 | 0.0507 |
Entamoeba histolytica | hypothetical protein | 0.1023 | 0.2573 | 1 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.1023 | 0.2573 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.05 | 0.0507 | 0.0507 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.05 | 0.0507 | 0.0507 |
Echinococcus granulosus | cyclin dependent kinase | 0.05 | 0.0507 | 0.0507 |
Brugia malayi | cell division control protein 2 homolog | 0.05 | 0.0507 | 0.126 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.05 | 0.0507 | 0.0507 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.05 | 0.0507 | 0.197 |
Loa Loa (eye worm) | hypothetical protein | 0.139 | 0.4022 | 0.4022 |
Entamoeba histolytica | protein kinase domain containing protein | 0.1023 | 0.2573 | 1 |
Schistosoma mansoni | cyclin-dependent kinase 5 activator | 0.2903 | 1 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.05 | 0.0507 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2903 | 1 | 1 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.05 | 0.0507 | 0.197 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.1023 | 0.2573 | 0.2573 |
Giardia lamblia | Kinase, CMGC CDK | 0.05 | 0.0507 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.0445 | 0.0445 |
Trichomonas vaginalis | CMGC family protein kinase | 0.05 | 0.0507 | 1 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.1023 | 0.2573 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1007 | 0.2511 | 0.2511 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.05 | 0.0507 | 0.0507 |
Echinococcus multilocularis | cyclin dependent kinase | 0.05 | 0.0507 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.139 | 0.4022 | 0.4022 |
Schistosoma mansoni | serine/threonine protein kinase | 0.05 | 0.0507 | 0.0507 |
Brugia malayi | Protein kinase domain containing protein | 0.05 | 0.0507 | 0.126 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.05 | 0.0507 | 0.0507 |
Brugia malayi | hypothetical protein | 0.139 | 0.4022 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.05 | 0.0507 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1023 | 0.2573 | 0.2573 |
Echinococcus granulosus | dual specificity | 0.1023 | 0.2573 | 0.2573 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.05 | 0.0507 | 0.197 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.05 | 0.0507 | 0.197 |
Plasmodium vivax | protein kinase Crk2 | 0.05 | 0.0507 | 0.5 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.1023 | 0.2573 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.05 | 0.0507 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.