Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0099 | 0.051 | 0.0417 |
Trichomonas vaginalis | cyclins, putative | 0.0137 | 0.2062 | 1 |
Trichomonas vaginalis | cyclin D, putative | 0.0099 | 0.051 | 0.2102 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0089 | 0.0097 | 0.0097 |
Echinococcus multilocularis | cyclins | 0.0099 | 0.051 | 0.0417 |
Brugia malayi | Protein kinase domain containing protein | 0.0181 | 0.3842 | 0.3781 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0137 | 0.2062 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0137 | 0.2062 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.2062 | 0.2062 |
Trichomonas vaginalis | cyclin B3, putative | 0.0099 | 0.051 | 0.2102 |
Echinococcus multilocularis | cyclin B | 0.0137 | 0.2062 | 0.1985 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0099 | 0.051 | 0.051 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0089 | 0.0097 | 0.0097 |
Trichomonas vaginalis | cyclin B, putative | 0.0137 | 0.2062 | 1 |
Echinococcus multilocularis | cyclins | 0.0099 | 0.051 | 0.0417 |
Echinococcus granulosus | cyclins | 0.0099 | 0.051 | 0.0417 |
Trichomonas vaginalis | cyclin B, putative | 0.0137 | 0.2062 | 1 |
Trichomonas vaginalis | cyclin D, putative | 0.0099 | 0.051 | 0.2102 |
Giardia lamblia | Hypothetical protein | 0.0099 | 0.051 | 0.2102 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0099 | 0.051 | 0.0417 |
Trichomonas vaginalis | cyclins, putative | 0.0137 | 0.2062 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0137 | 0.2062 | 1 |
Onchocerca volvulus | 0.0137 | 0.2062 | 0.5 | |
Schistosoma mansoni | cyclin d | 0.0331 | 1 | 1 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0137 | 0.2062 | 1 |
Echinococcus multilocularis | cyclin b3 | 0.0099 | 0.051 | 0.0417 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0137 | 0.2062 | 0.1985 |
Echinococcus granulosus | cyclins | 0.0099 | 0.051 | 0.0417 |
Giardia lamblia | Cyclin A | 0.0099 | 0.051 | 0.2102 |
Echinococcus multilocularis | cyclins | 0.0099 | 0.051 | 0.0417 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0089 | 0.0097 | 0.0097 |
Trichomonas vaginalis | cyclins, putative | 0.0137 | 0.2062 | 1 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0137 | 0.2062 | 1 |
Schistosoma mansoni | cyclin B3 | 0.0099 | 0.051 | 0.0417 |
Entamoeba histolytica | cyclin family protein | 0.0099 | 0.051 | 0.2102 |
Trichomonas vaginalis | cyclin A, putative | 0.0137 | 0.2062 | 1 |
Plasmodium vivax | protein kinase Crk2 | 0.0089 | 0.0097 | 0.5 |
Echinococcus granulosus | cyclin B3 1 | 0.0099 | 0.051 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.2062 | 0.2062 |
Plasmodium falciparum | cyclin | 0.0099 | 0.051 | 1 |
Echinococcus granulosus | cyclin b3 | 0.0099 | 0.051 | 0.0417 |
Echinococcus granulosus | cyclins | 0.0099 | 0.051 | 0.0417 |
Loa Loa (eye worm) | CAMK/CAMKL/CHK1 protein kinase | 0.0181 | 0.3842 | 0.3842 |
Trichomonas vaginalis | cyclins, putative | 0.0099 | 0.051 | 0.2102 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.0331 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0331 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0099 | 0.051 | 0.0417 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0137 | 0.2062 | 0.1985 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0089 | 0.0097 | 0.5 |
Echinococcus granulosus | cyclins | 0.0099 | 0.051 | 0.0417 |
Echinococcus granulosus | cyclins | 0.0099 | 0.051 | 0.0417 |
Echinococcus multilocularis | cyclins | 0.0099 | 0.051 | 0.0417 |
Entamoeba histolytica | cyclin, putative | 0.0137 | 0.2062 | 1 |
Echinococcus multilocularis | cyclin B3 1 | 0.0099 | 0.051 | 0.0417 |
Echinococcus multilocularis | cyclins | 0.0099 | 0.051 | 0.0417 |
Leishmania major | cyclin | 0.0137 | 0.2062 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0099 | 0.051 | 0.2102 |
Echinococcus multilocularis | cyclins | 0.0099 | 0.051 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0307 | 0.9018 | 0.9018 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.0331 | 1 | 1 |
Echinococcus granulosus | cyclin B | 0.0137 | 0.2062 | 0.1985 |
Trypanosoma cruzi | cyclin 6, putative | 0.0137 | 0.2062 | 1 |
Entamoeba histolytica | cyclin family protein | 0.0099 | 0.051 | 0.2102 |
Entamoeba histolytica | cyclin, putative | 0.0099 | 0.051 | 0.2102 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0181 | 0.3842 | 0.3781 |
Schistosoma mansoni | cyclin B | 0.0137 | 0.2062 | 0.1985 |
Trichomonas vaginalis | cyclin B, putative | 0.0099 | 0.051 | 0.2102 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0099 | 0.051 | 0.0417 |
Trichomonas vaginalis | cyclins, putative | 0.0137 | 0.2062 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0137 | 0.2062 | 1 |
Schistosoma mansoni | cyclins | 0.0099 | 0.051 | 0.0417 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0137 | 0.2062 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0137 | 0.2062 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.