Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0174 | 0.1711 | 0.5 |
Trypanosoma cruzi | prolyl endopeptidase | 0.043 | 0.6925 | 0.6315 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.1711 | 0.5 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0217 | 0.2589 | 0.3739 |
Trypanosoma brucei | metacaspase MCA3 | 0.0581 | 1 | 1 |
Echinococcus multilocularis | caspase 2 | 0.0217 | 0.2589 | 0.1684 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.1711 | 0.5 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0171 | 0.1654 | 0.5 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.043 | 0.6925 | 1 |
Toxoplasma gondii | PAN domain-containing protein | 0.033 | 0.489 | 0.3835 |
Trypanosoma cruzi | metacaspase, putative | 0.0581 | 1 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.043 | 0.6925 | 1 |
Echinococcus granulosus | caspase 2 | 0.0217 | 0.2589 | 0.1684 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.1711 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0174 | 0.1711 | 0.5 |
Echinococcus multilocularis | prolyl endopeptidase | 0.043 | 0.6925 | 1 |
Toxoplasma gondii | PAN domain-containing protein | 0.033 | 0.489 | 0.3835 |
Trypanosoma brucei | metacaspase 5, putative | 0.0581 | 1 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0174 | 0.1711 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.1711 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0174 | 0.1711 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0174 | 0.1711 | 0.5 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0581 | 1 | 1 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0581 | 1 | 1 |
Trypanosoma cruzi | metacaspase, putative | 0.0581 | 1 | 1 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0171 | 0.1654 | 0.5 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0581 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.6925 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0174 | 0.1711 | 0.5 |
Trypanosoma cruzi | metacaspase, putative | 0.0581 | 1 | 1 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.043 | 0.6925 | 1 |
Onchocerca volvulus | 0.0119 | 0.0592 | 0.0856 | |
Trypanosoma brucei | Metacaspase-4 | 0.0174 | 0.1711 | 0.0068 |
Brugia malayi | Cell death protein 3 precursor | 0.0217 | 0.2589 | 0.3153 |
Echinococcus granulosus | prolyl endopeptidase | 0.043 | 0.6925 | 1 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0174 | 0.1711 | 0.1766 |
Trypanosoma cruzi | metacaspase, putative | 0.0581 | 1 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0174 | 0.1711 | 0.5 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0174 | 0.1711 | 0.1766 |
Toxoplasma gondii | prolyl endopeptidase | 0.043 | 0.6925 | 0.629 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0174 | 0.1711 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.043 | 0.6925 | 1 |
Trypanosoma brucei | metacaspase MCA2 | 0.0581 | 1 | 1 |
Trypanosoma brucei | metacaspase | 0.0174 | 0.1711 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.2589 | 0.3153 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.1711 | 0.1766 |
Plasmodium falciparum | metacaspase 1 | 0.0581 | 1 | 1 |
Trypanosoma brucei | prolyl endopeptidase | 0.043 | 0.6925 | 0.6315 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.043 | 0.6925 | 0.6315 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0217 | 0.2589 | 0.3153 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.1711 | 0.5 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0174 | 0.1711 | 0.1766 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0174 | 0.1711 | 0.1766 |
Plasmodium vivax | metacaspase 1, putative | 0.0581 | 1 | 1 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0385 | 0.6007 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.1711 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0174 | 0.1711 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.