Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Histone deacetylase family protein | 0.0604 | 0.9751 | 1 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0548 | 0.8636 | 0.6226 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0548 | 0.8636 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0548 | 0.8636 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.3135 | 0.2101 |
Trypanosoma brucei | histone deacetylase 1 | 0.0548 | 0.8636 | 0.8315 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.4578 | 0.3824 |
Echinococcus granulosus | histone deacetylase 3 | 0.0548 | 0.8636 | 0.8636 |
Echinococcus granulosus | histone deacetylase 6 | 0.0604 | 0.9751 | 0.9751 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0604 | 0.9751 | 1 |
Echinococcus granulosus | histone deacetylase 8 | 0.0272 | 0.3135 | 0.3135 |
Loa Loa (eye worm) | histone deacetylase | 0.0604 | 0.9751 | 1 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0548 | 0.8636 | 0.6226 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0548 | 0.8636 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0604 | 0.9751 | 1 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0604 | 0.9751 | 0.9751 |
Echinococcus granulosus | histone deacetylase 1 | 0.0548 | 0.8636 | 0.8636 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0548 | 0.8636 | 0.8315 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0548 | 0.8636 | 0.5 |
Echinococcus granulosus | histone deacetylase 6 | 0.0604 | 0.9751 | 0.9751 |
Leishmania major | histone deacetylase, putative | 0.0604 | 0.9751 | 1 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0604 | 0.9751 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0548 | 0.8636 | 0.5 |
Schistosoma mansoni | histone deacetylase | 0.0548 | 0.8636 | 0.8636 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0604 | 0.9751 | 1 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0548 | 0.8636 | 0.8669 |
Leishmania major | histone deacetylase, putative | 0.0604 | 0.9751 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0604 | 0.9751 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0548 | 0.8636 | 0.8315 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0548 | 0.8636 | 0.8669 |
Plasmodium vivax | histone deacetylase, putative | 0.0604 | 0.9751 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0617 | 1 | 1 |
Entamoeba histolytica | histone deacetylase, putative | 0.0548 | 0.8636 | 0.5 |
Echinococcus granulosus | histone deacetylase 7 | 0.0604 | 0.9751 | 0.9751 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0548 | 0.8636 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0548 | 0.8636 | 0.8315 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0272 | 0.3135 | 0.3135 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0272 | 0.3135 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0456 | 0.6797 | 0.6473 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0548 | 0.8636 | 0.5 |
Brugia malayi | Histone deacetylase 1 | 0.0548 | 0.8636 | 0.6226 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.0456 | 0.6797 | 0.5534 |
Trypanosoma brucei | histone deacetylase 4 | 0.0604 | 0.9751 | 1 |
Trypanosoma brucei | histone deacetylase 3 | 0.0604 | 0.9751 | 1 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0272 | 0.3135 | 0.3135 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0604 | 0.9751 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0604 | 0.9751 | 0.9751 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0548 | 0.8636 | 0.8636 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0548 | 0.8636 | 0.6226 |
Plasmodium falciparum | histone deacetylase 2 | 0.0604 | 0.9751 | 1 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0604 | 0.9751 | 0.9751 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0604 | 0.9751 | 0.9751 |
Plasmodium falciparum | histone deacetylase, putative | 0.0604 | 0.9751 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0548 | 0.8636 | 0.8636 |
Brugia malayi | Histone deacetylase family protein | 0.0604 | 0.9751 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0548 | 0.8636 | 0.5 |
Trypanosoma brucei | histone deacetylase, putative | 0.0604 | 0.9751 | 1 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0272 | 0.3135 | 0.3135 |
Giardia lamblia | Histone deacetylase | 0.0548 | 0.8636 | 0.5 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0548 | 0.8636 | 0.8636 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0548 | 0.8636 | 0.8315 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0617 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0548 | 0.8636 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0548 | 0.8636 | 0.8669 |
Echinococcus granulosus | histone deacetylase | 0.0604 | 0.9751 | 0.9751 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0604 | 0.9751 | 0.9751 |
Echinococcus multilocularis | histone deacetylase | 0.0604 | 0.9751 | 0.9751 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.4329 | 0.3527 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.