Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Peroxidasin homolog | 0.0056 | 0.0562 | 0.5 |
Brugia malayi | hypothetical protein | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0056 | 0.0562 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0056 | 0.0562 | 1 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0003 | 0.0002 | 0.0002 |
Onchocerca volvulus | 0.0056 | 0.0562 | 0.5 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0056 | 0.0562 | 1 |
Schistosoma mansoni | peroxidasin | 0.0056 | 0.0562 | 0.0562 |
Schistosoma mansoni | transient receptor potential channel | 0.0003 | 0.0002 | 0.0002 |
Brugia malayi | Animal haem peroxidase family protein | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0056 | 0.0562 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0056 | 0.0562 | 0.0562 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0003 | 0.0002 | 0.004 |
Schistosoma mansoni | peroxidasin | 0.0056 | 0.0562 | 0.0562 |
Onchocerca volvulus | Peroxidase homolog | 0.0056 | 0.0562 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0003 | 0.0002 | 0.0002 |
Echinococcus multilocularis | ankyrin repeat protein | 0.0279 | 0.2904 | 0.2904 |
Onchocerca volvulus | Dual oxidase homolog | 0.0056 | 0.0562 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0003 | 0.0002 | 0.0002 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0954 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.0279 | 0.2904 | 0.2904 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0282 | 0.2936 | 0.2936 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0003 | 0.0002 | 0.0002 |
Brugia malayi | Animal haem peroxidase family protein | 0.0056 | 0.0562 | 1 |
Onchocerca volvulus | 0.0056 | 0.0562 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0282 | 0.2934 | 0.2934 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0056 | 0.0562 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0056 | 0.0562 | 0.5 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0954 | 1 | 1 |
Echinococcus granulosus | peroxidasin | 0.0056 | 0.0562 | 0.0562 |
Brugia malayi | Peroxidasin | 0.0056 | 0.0562 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0056 | 0.0562 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0056 | 0.0562 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Onchocerca volvulus | 0.0056 | 0.0562 | 0.5 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0562 | 1 |
Echinococcus granulosus | ankyrin repeat protein | 0.0279 | 0.2904 | 0.2904 |
Brugia malayi | Blistered cuticle protein 3 | 0.0056 | 0.0562 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.