Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | apical sushi protein, putative | 0.0047 | 0.225 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1334 | 0.1334 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.2185 | 0.971 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0042 | 0.1911 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0221 | 0.0221 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.2185 | 0.971 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.1911 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0042 | 0.1911 | 0.8493 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0047 | 0.225 | 0.9057 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2185 | 0.2185 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0042 | 0.1911 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0221 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0042 | 0.1911 | 1 |
Loa Loa (eye worm) | pregnancy-associated plasma protein-E | 0.0047 | 0.225 | 0.855 |
Echinococcus multilocularis | C type lectin domian containing protein | 0.0047 | 0.225 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.2185 | 0.971 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.2484 | 0.9441 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.1911 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2185 | 0.2185 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.1911 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.1911 | 0.1728 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.2185 | 0.971 |
Toxoplasma gondii | rhoptry neck protein RON1 | 0.0047 | 0.225 | 1 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Brugia malayi | Sushi domain | 0.0047 | 0.225 | 0.9057 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Loa Loa (eye worm) | inositol-1 | 0.0042 | 0.1911 | 0.7262 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0042 | 0.1911 | 1 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.1911 | 0.1911 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0221 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0042 | 0.1911 | 0.8493 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0221 | 0.084 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.1911 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1334 | 0.5371 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Brugia malayi | pregnancy-associated plasma protein-A | 0.0047 | 0.225 | 0.9057 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Brugia malayi | Inositol-1 | 0.0042 | 0.1911 | 0.7692 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2185 | 0.2185 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Echinococcus granulosus | c4b binding protein beta chain | 0.0047 | 0.225 | 1 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1334 | 0.5071 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Toxoplasma gondii | rhoptry neck protein RON9 | 0.0047 | 0.225 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Plasmodium falciparum | apical sushi protein | 0.0047 | 0.225 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.2185 | 0.8302 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.1911 | 0.1911 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.2484 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2632 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.2185 | 0.8794 |
Echinococcus granulosus | C type lectin domian containing protein | 0.0047 | 0.225 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0221 | 0.0983 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Schistosoma mansoni | c4b-binding protein beta chain | 0.0047 | 0.225 | 0.225 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0038 | 0.159 | 0.5 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0042 | 0.1911 | 0.8329 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.2484 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.1911 | 1 |
Echinococcus multilocularis | c4b binding protein beta chain | 0.0047 | 0.225 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0221 | 0.089 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.2484 | 0.9441 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0221 | 0.0221 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0221 | 0.0983 |
Trypanosoma brucei | RNA helicase, putative | 0.0153 | 1 | 1 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0038 | 0.159 | 1 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.