Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | c4b binding protein beta chain | 0.0047 | 0.225 | 1 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Brugia malayi | pregnancy-associated plasma protein-A | 0.0047 | 0.225 | 0.9057 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0042 | 0.1911 | 1 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0221 | 0.5 |
Trypanosoma brucei | RNA helicase, putative | 0.0153 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0042 | 0.1911 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2632 | 1 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.2484 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.2484 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.2484 | 0.9441 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0042 | 0.1911 | 1 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2185 | 0.2185 |
Toxoplasma gondii | rhoptry neck protein RON1 | 0.0047 | 0.225 | 1 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2185 | 0.2185 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.1911 | 1 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0038 | 0.159 | 0.5 |
Plasmodium falciparum | apical sushi protein | 0.0047 | 0.225 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.1911 | 0.1728 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1334 | 0.1334 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.2185 | 0.8302 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0221 | 0.089 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.2185 | 0.971 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Brugia malayi | Inositol-1 | 0.0042 | 0.1911 | 0.7692 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0221 | 0.0983 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.1911 | 1 |
Echinococcus multilocularis | C type lectin domian containing protein | 0.0047 | 0.225 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0221 | 0.0221 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.2484 | 0.9441 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.2185 | 0.971 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0042 | 0.1911 | 0.8493 |
Echinococcus multilocularis | c4b binding protein beta chain | 0.0047 | 0.225 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0221 | 0.5 |
Toxoplasma gondii | rhoptry neck protein RON9 | 0.0047 | 0.225 | 1 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0221 | 0.0221 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1334 | 0.5071 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.1911 | 1 |
Loa Loa (eye worm) | inositol-1 | 0.0042 | 0.1911 | 0.7262 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0038 | 0.159 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.2185 | 0.971 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Brugia malayi | Sushi domain | 0.0047 | 0.225 | 0.9057 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1334 | 0.5371 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0221 | 0.084 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.2185 | 0.971 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2185 | 0.2185 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.1911 | 1 |
Onchocerca volvulus | 0.0047 | 0.225 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.225 | 0.855 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Plasmodium vivax | apical sushi protein, putative | 0.0047 | 0.225 | 1 |
Echinococcus granulosus | C type lectin domian containing protein | 0.0047 | 0.225 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.1911 | 1 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0047 | 0.225 | 0.9057 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.1911 | 0.1911 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0042 | 0.1911 | 0.8329 |
Schistosoma mansoni | c4b-binding protein beta chain | 0.0047 | 0.225 | 0.225 |
Loa Loa (eye worm) | pregnancy-associated plasma protein-E | 0.0047 | 0.225 | 0.855 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0042 | 0.1911 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.2185 | 0.8794 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0042 | 0.1911 | 0.8493 |
Brugia malayi | hypothetical protein | 0.0047 | 0.225 | 0.9057 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0221 | 0.0983 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.1911 | 0.1911 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.