Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Schistosoma mansoni | cytochrome c oxidase subunit II | 0.0383 | 0.7936 | 1 |
Schistosoma mansoni | cytochrome oxidase subunit | 0.0167 | 0.2692 | 0.314 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Schistosoma mansoni | cytochrome oxidase subunit | 0.0167 | 0.2692 | 0.314 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0308 | 0.6126 | 1 |
Schistosoma mansoni | cytochrome-c oxidase | 0.0141 | 0.2064 | 0.2318 |
Onchocerca volvulus | Peroxidase homolog | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Schistosoma mansoni | peroxidasin | 0.0308 | 0.6126 | 0.7632 |
Onchocerca volvulus | Cytochrome c oxidase subunit 1 homolog | 0.0167 | 0.2692 | 0.1547 |
Brugia malayi | hypothetical protein | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | 0.0167 | 0.2692 | 0.1547 | |
Mycobacterium tuberculosis | Probable cytochrome C oxidase polypeptide I CtaD (cytochrome AA3 subunit 1) | 0.0167 | 0.2692 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | 0.0308 | 0.6126 | 1 | |
Wolbachia endosymbiont of Brugia malayi | cytochrome c oxidase, subunit 2 | 0.0467 | 1 | 1 |
Echinococcus granulosus | peroxidasin | 0.0308 | 0.6126 | 0.4699 |
Brugia malayi | Animal haem peroxidase family protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | cytochrome oxidase subunit 2 | 0.0085 | 0.0689 | 0.1124 |
Brugia malayi | cytochrome c oxidase subunit I | 0.0068 | 0.0292 | 0.0476 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Mycobacterium leprae | PROBABLE CYTOCHROME C OXIDASE POLYPEPTIDE I CTAD (CYTOCHROME AA3 SUBUNIT 1) | 0.0167 | 0.2692 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.0308 | 0.6126 | 1 |
Brugia malayi | Peroxidasin | 0.0308 | 0.6126 | 1 |
Schistosoma mansoni | cytochrome oxidase subunit | 0.0167 | 0.2692 | 0.314 |
Plasmodium vivax | conserved Plasmodium protein, unknown function | 0.0326 | 0.6561 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0308 | 0.6126 | 1 |
Plasmodium vivax | cytochrome c oxidase subunit I | 0.0167 | 0.2692 | 0.1398 |
Brugia malayi | Animal haem peroxidase family protein | 0.0308 | 0.6126 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Toxoplasma gondii | cytochrome C oxidase subunit IIb, putative | 0.0141 | 0.2064 | 0.5 |
Onchocerca volvulus | 0.0308 | 0.6126 | 1 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0308 | 0.6126 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0308 | 0.6126 | 0.5 |
Onchocerca volvulus | 0.0308 | 0.6126 | 1 | |
Schistosoma mansoni | peroxidasin | 0.0308 | 0.6126 | 0.7632 |
Mycobacterium ulcerans | cytochrome C oxidase polypeptide I CtaD | 0.0167 | 0.2692 | 1 |
Mycobacterium ulcerans | cytochrome C oxidase polypeptide I CtaD | 0.0167 | 0.2692 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0308 | 0.6126 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0308 | 0.6126 | 1 |
Schistosoma mansoni | cytochrome oxidase subunit | 0.0167 | 0.2692 | 0.314 |
Loa Loa (eye worm) | cytochrome c oxidase subunit I | 0.0068 | 0.0292 | 0.0476 |
Plasmodium falciparum | cytochrome c oxidase subunit 1 | 0.0167 | 0.2692 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.