Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0211 | 0.5 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0211 | 0.5 | 0.5 |
Leishmania major | monoglyceride lipase, putative | 0.0211 | 0.5 | 0.5 |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.0211 | 0.5 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0211 | 0.5 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0211 | 0.5 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0211 | 0.5 | 0.5 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.0211 | 0.5 | 0.5 |
Mycobacterium ulcerans | lysophospholipase | 0.0211 | 0.5 | 0.5 |
Plasmodium vivax | PST-A protein | 0.0211 | 0.5 | 0.5 |
Plasmodium falciparum | esterase, putative | 0.0211 | 0.5 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0211 | 0.5 | 0.5 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.0211 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0211 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0211 | 0.5 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0211 | 0.5 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0211 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible lysophospholipase | 0.0211 | 0.5 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0211 | 0.5 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0211 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0211 | 0.5 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0211 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.