Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 0.2397 | 1 |
Brugia malayi | Hint module family protein | 0.0269 | 0.2397 | 1 |
Schistosoma mansoni | hypothetical protein | 0.072 | 0.7165 | 1 |
Echinococcus granulosus | polyADP ribose glycohydrolase | 0.012 | 0.0824 | 0.0824 |
Trypanosoma cruzi | poly(ADP-ribose) glycohydrolase, putative | 0.012 | 0.0824 | 1 |
Loa Loa (eye worm) | Poly(ADP-ribose) glycohydrolase | 0.012 | 0.0824 | 0.3425 |
Echinococcus multilocularis | poly(ADP ribose) glycohydrolase | 0.012 | 0.0824 | 0.0824 |
Echinococcus granulosus | cAMP dependent protein kinase catalytic subunit | 0.0042 | 0.0005 | 0.0005 |
Trypanosoma cruzi | poly(ADP-ribose) glycohydrolase, putative | 0.012 | 0.0824 | 1 |
Brugia malayi | Hint module family protein | 0.0269 | 0.2397 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0053 | 0.0124 | 0.1454 |
Brugia malayi | Poly | 0.012 | 0.0824 | 0.3425 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0042 | 0.0005 | 0.0005 |
Echinococcus multilocularis | hedgehog | 0.0989 | 1 | 1 |
Leishmania major | protein kinase A catalytic subunit | 0.0042 | 0.0005 | 0.5 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0042 | 0.0005 | 0.0005 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0042 | 0.0005 | 0.0005 |
Echinococcus granulosus | cAMP dependent protein kinase catalytic subunit | 0.0042 | 0.0005 | 0.0005 |
Plasmodium falciparum | cAMP-dependent protein kinase catalytic subunit | 0.0042 | 0.0005 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 0.2397 | 1 |
Toxoplasma gondii | poly(ADP-ribose) glycohydrolase | 0.0053 | 0.0124 | 0.1454 |
Plasmodium vivax | cAMP-dependent protein kinase catalytic subunit, putative | 0.0042 | 0.0005 | 0.5 |
Toxoplasma gondii | poly(ADP-ribose) glycohydrolase | 0.012 | 0.0824 | 1 |
Echinococcus granulosus | cAMP dependent protein kinase catalytic subunit | 0.0042 | 0.0005 | 0.0005 |
Entamoeba histolytica | poly(ADP-ribose) glycohydrolase, putative | 0.0053 | 0.0124 | 0.1454 |
Schistosoma mansoni | poly(ADP-ribose) glycohydrolase | 0.012 | 0.0824 | 0.1144 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0.0005 | 0.5 |
Leishmania major | protein kinase A catalytic subunit isoform 2 | 0.0042 | 0.0005 | 0.5 |
Entamoeba histolytica | poly(ADP-ribose) glycohydrolase, putative | 0.012 | 0.0824 | 1 |
Giardia lamblia | Kinase, AGC PKA | 0.0042 | 0.0005 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.012 | 0.0824 | 1 |
Trypanosoma brucei | poly(ADP-ribose) glycohydrolase, putative | 0.012 | 0.0824 | 1 |
Leishmania major | protein kinase A catalytic subunit isoform 1 | 0.0042 | 0.0005 | 0.5 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0042 | 0.0005 | 0.0005 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.