Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | thymidylate kinase | 0.0125 | 0.5307 | 1 |
Trypanosoma cruzi | adenylate kinase, putative | 0.0072 | 0.1599 | 0.3013 |
Trypanosoma cruzi | adenylate kinase, putative | 0.0053 | 0.0255 | 0.048 |
Plasmodium vivax | thymidylate kinase, putative | 0.0125 | 0.5307 | 1 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0125 | 0.5307 | 0.5 |
Trypanosoma cruzi | adenylate kinase 2 | 0.0053 | 0.0255 | 0.048 |
Leishmania major | adenylate kinase, putative | 0.0136 | 0.6105 | 1 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0125 | 0.5307 | 0.5 |
Trypanosoma cruzi | adenylate kinase, putative | 0.0072 | 0.1599 | 0.3013 |
Mycobacterium ulcerans | thymidylate kinase | 0.0125 | 0.5307 | 0.5 |
Treponema pallidum | thymidylate kinase (tmk) | 0.0125 | 0.5307 | 1 |
Echinococcus multilocularis | thymidylate kinase | 0.0125 | 0.5307 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.5307 | 0.4413 |
Plasmodium falciparum | GTP:AMP phosphotransferase | 0.0088 | 0.2718 | 0.3018 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0125 | 0.5307 | 0.5 |
Toxoplasma gondii | thymidylate kinase | 0.0125 | 0.5307 | 1 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0125 | 0.5307 | 1 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0125 | 0.5307 | 1 |
Leishmania major | adenylate kinase, putative | 0.0072 | 0.1599 | 0.2619 |
Plasmodium vivax | adenylate kinase 1, putative | 0.0088 | 0.2718 | 0.3018 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0125 | 0.5307 | 1 |
Chlamydia trachomatis | thymidylate kinase | 0.0125 | 0.5307 | 0.5 |
Leishmania major | adenylate kinase 2 | 0.0053 | 0.0255 | 0.0417 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0125 | 0.5307 | 1 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0125 | 0.5307 | 1 |
Giardia lamblia | CDC8 | 0.0125 | 0.5307 | 0.5 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0125 | 0.5307 | 0.5 |
Echinococcus granulosus | thymidylate kinase | 0.0125 | 0.5307 | 1 |
Loa Loa (eye worm) | thymidylate kinase | 0.0125 | 0.5307 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | thymidylate kinase | 0.0125 | 0.5307 | 0.5 |
Schistosoma mansoni | thymidylate kinase | 0.0125 | 0.5307 | 0.4413 |
Trypanosoma brucei | adenylate kinase, putative | 0.0072 | 0.1599 | 0.2661 |
Leishmania major | thymidylate kinase-like protein | 0.0125 | 0.5307 | 0.8692 |
Brugia malayi | thymidylate kinase | 0.0125 | 0.5307 | 0.5 |
Schistosoma mansoni | thymidylate kinase | 0.0125 | 0.5307 | 0.4413 |
Toxoplasma gondii | adenylate kinase | 0.0088 | 0.2718 | 0.3018 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0125 | 0.5307 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.