Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0285 | 0 | 0.5 |
Entamoeba histolytica | aminopeptidase, putative | 0.0285 | 0 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0285 | 0 | 0.5 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0783 | 0.7295 | 0.8549 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0285 | 0 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0511 | 0.3306 | 0.3306 |
Echinococcus multilocularis | aminopeptidase N | 0.0968 | 1 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0285 | 0 | 0.5 |
Onchocerca volvulus | 0.0968 | 1 | 1 | |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0285 | 0 | 0.5 |
Echinococcus granulosus | aminopeptidase N | 0.0968 | 1 | 1 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0285 | 0 | 0.5 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0285 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0868 | 0.8533 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0683 | 0.5828 | 0.683 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0285 | 0 | 0.5 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0285 | 0 | 0.5 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0285 | 0 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0285 | 0 | 0.5 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0285 | 0 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0285 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.