Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | Rho-associated, coiled-coil containing protein kinase 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Sodium:solute symporter family protein | 0.0744 | 0.2074 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0744 | 0.2074 | 1 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0744 | 0.2074 | 0.2074 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.2917 | 1 | 1 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.2917 | 1 | 1 |
Schistosoma mansoni | high-affinity choline transporter | 0.0744 | 0.2074 | 0.2074 |
Echinococcus multilocularis | solute carrier family 5 | 0.2917 | 1 | 1 |
Echinococcus granulosus | solute carrier family 5 | 0.2917 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0744 | 0.2074 | 1 |
Schistosoma mansoni | inositol transporter | 0.2917 | 1 | 1 |
Schistosoma mansoni | inositol transporter | 0.2917 | 1 | 1 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.2917 | 1 | 1 |
Onchocerca volvulus | 0.0744 | 0.2074 | 1 | |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.2917 | 1 | 1 |
Schistosoma mansoni | sodium/solute symporter | 0.0744 | 0.2074 | 0.2074 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0744 | 0.2074 | 0.5 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0744 | 0.2074 | 0.2074 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0744 | 0.2074 | 0.2074 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0744 | 0.2074 | 0.2074 |
Brugia malayi | GH02984p | 0.0744 | 0.2074 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.