Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Dynamin | 0.0038 | 1 | 1 |
Schistosoma mansoni | dynamin | 0.0038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 1 | 1 |
Toxoplasma gondii | dynamin-related protein DRPB | 0.0036 | 0.9006 | 1 |
Trichomonas vaginalis | dynamin, putative | 0.0036 | 0.9006 | 0.5 |
Plasmodium falciparum | dynamin-like protein | 0.0036 | 0.9006 | 0.5 |
Entamoeba histolytica | dynamin-1-like protein, putative | 0.0036 | 0.9006 | 1 |
Trichomonas vaginalis | dynamin, putative | 0.0036 | 0.9006 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.0036 | 0.9006 | 0.5 |
Plasmodium falciparum | dynamin-like protein | 0.0036 | 0.9006 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.0036 | 0.9006 | 0.5 |
Trichomonas vaginalis | interferon-induced GTP-binding protein mx, putative | 0.0036 | 0.9006 | 0.5 |
Toxoplasma gondii | dynamin-related protein DRPA | 0.0036 | 0.9006 | 1 |
Trypanosoma brucei | dynamin-1-like protein | 0.0036 | 0.9006 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.0036 | 0.9006 | 0.5 |
Trichomonas vaginalis | mgm1, putative | 0.0036 | 0.9006 | 0.5 |
Leishmania major | GTP-binding protein, putative | 0.0036 | 0.9006 | 0.5 |
Trypanosoma cruzi | dynamin-1-like protein | 0.0036 | 0.9006 | 0.5 |
Trypanosoma brucei | dynamin-1-like protein | 0.0036 | 0.9006 | 0.5 |
Schistosoma mansoni | dynamin | 0.0038 | 1 | 1 |
Giardia lamblia | Dynamin | 0.0036 | 0.9006 | 0.5 |
Plasmodium vivax | dynamin protein, putative | 0.0036 | 0.9006 | 0.5 |
Entamoeba histolytica | dynamin-like protein | 0.0036 | 0.9006 | 1 |
Plasmodium vivax | dynamin-like protein, putative | 0.0036 | 0.9006 | 0.5 |
Schistosoma mansoni | dynamin | 0.0036 | 0.9006 | 0.5718 |
Echinococcus granulosus | dynamin 1 | 0.0038 | 1 | 1 |
Trichomonas vaginalis | dynamin, putative | 0.0036 | 0.9006 | 0.5 |
Echinococcus multilocularis | dynamin 1 | 0.0038 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 52.66 % | Activity at human carbonic anhydrase 2 assessed as hydrolysis of p- nitrophenyl acetate at 0.3 umol/L at pH 7.6 | ChEMBL. | 21524585 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.