Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0146 | 0.0886 | 0.1279 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0146 | 0.0886 | 0.1279 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0146 | 0.0886 | 1 |
Entamoeba histolytica | aminopeptidase, putative | 0.0146 | 0.0886 | 0.5 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0146 | 0.0886 | 0.5 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0146 | 0.0886 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0497 | 0.6927 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0146 | 0.0886 | 1 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0403 | 0.5293 | 0.8762 |
Echinococcus granulosus | aminopeptidase N | 0.0497 | 0.6927 | 1 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0146 | 0.0886 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0146 | 0.0886 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0146 | 0.0886 | 1 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0146 | 0.0886 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0146 | 0.0886 | 0.1279 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0676 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0351 | 0.4407 | 0.7295 |
Onchocerca volvulus | 0.0497 | 0.6927 | 1 | |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0146 | 0.0886 | 0.5 |
Echinococcus multilocularis | aminopeptidase N | 0.0497 | 0.6927 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0446 | 0.6041 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0146 | 0.0886 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0146 | 0.0886 | 0.5 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0146 | 0.0886 | 0.1279 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0146 | 0.0886 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0146 | 0.0886 | 0.1279 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0146 | 0.0886 | 0.1279 |
Loa Loa (eye worm) | aminopeptidase N | 0.0146 | 0.0886 | 0.1467 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.