Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0644 | 0.0236 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0644 | 0.0236 | 0.5 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0644 | 0.0236 | 0.5 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0644 | 0.0236 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0577 | 0 | 0.5 |
Plasmodium falciparum | esterase, putative | 0.0577 | 0 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0577 | 0 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0577 | 0 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0577 | 0 | 0.5 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.0619 | 0.0148 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0577 | 0 | 0.5 |
Brugia malayi | amidase | 0.0644 | 0.0236 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0577 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0577 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0577 | 0 | 0.5 |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.0577 | 0 | 0.5 |
Leishmania major | monoglyceride lipase, putative | 0.0577 | 0 | 0.5 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0577 | 0 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0577 | 0 | 0.5 |
Schistosoma mansoni | amidase | 0.0644 | 0.0236 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0577 | 0 | 0.5 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0644 | 0.0236 | 0.5 |
Plasmodium vivax | PST-A protein | 0.0577 | 0 | 0.5 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.0577 | 0 | 0.5 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0577 | 0 | 0.5 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0644 | 0.0236 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0577 | 0 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0577 | 0 | 0.5 |
Mycobacterium ulcerans | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD | 0.3418 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.