Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0108 | 0.2089 | 0.2033 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0108 | 0.2089 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0108 | 0.2089 | 0.2033 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0108 | 0.2089 | 0.2033 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0108 | 0.2089 | 0.5 |
Onchocerca volvulus | 0.0108 | 0.2089 | 0.2089 | |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0108 | 0.2089 | 0.2033 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0108 | 0.2089 | 0.2033 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0108 | 0.2089 | 1 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0065 | 0.0774 | 0.0709 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0108 | 0.2089 | 0.2033 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0108 | 0.2089 | 0.5 |
Brugia malayi | Matrixin family protein | 0.0043 | 0.0109 | 0.0039 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0108 | 0.2089 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0108 | 0.2089 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0108 | 0.2089 | 0.2033 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0298 | 0.786 | 0.8892 |
Schistosoma mansoni | family M1 non-peptidase homologue (M01 family) | 0.007 | 0.0929 | 0.4252 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.007 | 0.008 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0108 | 0.2089 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0929 | 0.105 |
Loa Loa (eye worm) | aminopeptidase N | 0.0108 | 0.2089 | 0.2363 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0108 | 0.2089 | 1 |
Onchocerca volvulus | 0.0368 | 1 | 1 | |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.007 | 0.0929 | 0.0864 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0108 | 0.2089 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.007 | 0.008 |
Loa Loa (eye worm) | matrixin family protein | 0.0043 | 0.0109 | 0.0124 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0108 | 0.2089 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0108 | 0.2089 | 0.2033 |
Brugia malayi | hypothetical protein | 0.0108 | 0.2089 | 0.2033 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0108 | 0.2089 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0929 | 0.105 |
Echinococcus multilocularis | aminopeptidase N | 0.0368 | 1 | 1 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0065 | 0.0774 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.67 | 0.7579 |
Loa Loa (eye worm) | hypothetical protein | 0.033 | 0.884 | 1 |
Echinococcus granulosus | aminopeptidase N | 0.0368 | 1 | 1 |
Entamoeba histolytica | aminopeptidase, putative | 0.0108 | 0.2089 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0108 | 0.2089 | 0.2033 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0108 | 0.2089 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0108 | 0.2089 | 0.2033 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0108 | 0.2089 | 0.5 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.0043 | 0.0086 | 0.0076 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0108 | 0.2089 | 0.2033 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.