Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | histone deacetylase, putative | 0.1449 | 1 | 0.5 |
Brugia malayi | Histone deacetylase 1 | 0.1449 | 1 | 1 |
Echinococcus granulosus | histone deacetylase | 0.1414 | 0.9709 | 0.9474 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.1449 | 1 | 1 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.1449 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 3 | 0.1449 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1449 | 1 | 0.5 |
Trypanosoma brucei | histone deacetylase 4 | 0.1414 | 0.9709 | 0.9474 |
Brugia malayi | histone deacetylase 11 | 0.0777 | 0.4468 | 0.4468 |
Trypanosoma brucei | histone deacetylase 3 | 0.1414 | 0.9709 | 0.9474 |
Trypanosoma brucei | histone deacetylase, putative | 0.1414 | 0.9709 | 0.9474 |
Echinococcus granulosus | histone deacetylase 6 | 0.1444 | 0.9959 | 0.9926 |
Schistosoma mansoni | histone deacetylase | 0.1449 | 1 | 1 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0777 | 0.4468 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.1414 | 0.9709 | 0.9709 |
Entamoeba histolytica | histone deacetylase, putative | 0.1449 | 1 | 0.5 |
Plasmodium vivax | histone deacetylase 1, putative | 0.1449 | 1 | 1 |
Plasmodium falciparum | histone deacetylase 1 | 0.1449 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1414 | 0.9709 | 0.9474 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.1449 | 1 | 1 |
Trypanosoma brucei | histone deacetylase 1 | 0.1449 | 1 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.1414 | 0.9709 | 0.9709 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.1414 | 0.9709 | 0.9474 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1414 | 0.9709 | 0.9474 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1449 | 1 | 0.5 |
Echinococcus granulosus | histone deacetylase 6 | 0.1414 | 0.9709 | 0.9474 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1449 | 1 | 0.5 |
Plasmodium vivax | histone deacetylase, putative | 0.1414 | 0.9709 | 0.9474 |
Echinococcus multilocularis | histone deacetylase 1 | 0.1449 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 7 | 0.1414 | 0.9709 | 0.9474 |
Echinococcus multilocularis | histone deacetylase | 0.1414 | 0.9709 | 0.9474 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0777 | 0.4468 | 0.4468 |
Schistosoma mansoni | histone deacetylase | 0.1449 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1414 | 0.9709 | 0.9474 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1449 | 1 | 0.5 |
Loa Loa (eye worm) | histone deacetylase | 0.1414 | 0.9709 | 0.9709 |
Schistosoma mansoni | histone deacetylase hda2 | 0.1444 | 0.9959 | 0.9926 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.1414 | 0.9709 | 0.9474 |
Loa Loa (eye worm) | hypothetical protein | 0.0637 | 0.3319 | 0.3319 |
Echinococcus granulosus | histone deacetylase 6 | 0.1414 | 0.9709 | 0.9474 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.1449 | 1 | 1 |
Giardia lamblia | Histone deacetylase | 0.1449 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1414 | 0.9709 | 0.9474 |
Plasmodium vivax | histone deacetylase 2, putative | 0.1414 | 0.9709 | 0.9474 |
Echinococcus multilocularis | histone deacetylase 7 | 0.1414 | 0.9709 | 0.9474 |
Echinococcus granulosus | histone deacetylase 1 | 0.1449 | 1 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.1414 | 0.9709 | 0.9709 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1449 | 1 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.1414 | 0.9709 | 0.9474 |
Loa Loa (eye worm) | hypothetical protein | 0.0667 | 0.3569 | 0.3569 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1449 | 1 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.1449 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1449 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.1449 | 1 | 1 |
Leishmania major | histone deacetylase, putative | 0.1449 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1449 | 1 | 0.5 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0818 | 0.4807 | 0.0613 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1449 | 1 | 0.5 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1414 | 0.9709 | 0.9474 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1444 | 0.9959 | 0.9926 |
Echinococcus granulosus | histone deacetylase 3 | 0.1449 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.1449 | 1 | 1 |
Leishmania major | histone deacetylase, putative | 0.1449 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0777 | 0.4468 | 0.4468 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.