TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 281.268 | Formula: C11H15N5O4
H donors: 4 H acceptors: 6 LogP: -2.02 Rotable bonds: 1
Rule of 5 violations (Lipinski): 1
SMILES: O[C@@H]1[C@H](O)[C@H](O)[C@@H](O[C@H]1n1cnc2c1ncnc2N)C
InChi: 1S/C11H15N5O4/c1-4-6(17)7(18)8(19)11(20-4)16-3-15-5-9(12)13-2-14-10(5)16/h2-4,6-8,11,17-19H,1H3,(H2,12,13,14)/t4-,6+,7+,8+,11+/m0/s1
InChiKey: METOOOPOWVLDNT-JKHDZATESA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Onchocerca volvulus		0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Onchocerca volvulus		0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus multilocularis	serotonin receptor	0.0053	0.3694	1
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.004	0.1195	0.3236
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Brugia malayi	hypothetical protein	0.0053	0.3694	0.2838
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0053	0.3694	0.2838
Brugia malayi	Dopamine receptor	0.0053	0.3694	0.2838
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Brugia malayi	ORL1-like opioid receptor	0.0053	0.3694	0.2838
Echinococcus granulosus	tm gpcr rhodopsin	0.0053	0.3694	1
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0053	0.3694	0.2838
Echinococcus granulosus	neuropeptides capa receptor	0.0053	0.3694	1
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0053	0.3694	0.2838
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.004	0.1195	0.1195
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Brugia malayi	AKH receptor	0.0053	0.3694	0.2838
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0053	0.3694	1
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0053	0.3694	0.2838
Brugia malayi	putative neuropeptide receptor NPR1	0.0053	0.3694	0.2838
Echinococcus multilocularis	fmrfamide receptor	0.0053	0.3694	1
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0053	0.3694	0.3694
Echinococcus multilocularis	neuropeptide s receptor	0.0053	0.3694	1
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Brugia malayi	hypothetical protein	0.0053	0.3694	0.2838
Brugia malayi	G-protein coupled receptor	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus multilocularis	g protein coupled receptor	0.0053	0.3694	1
Brugia malayi	GnHR receptor homolog	0.0053	0.3694	0.2838
Brugia malayi	Serotonin receptor	0.0053	0.3694	0.2838
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.004	0.1195	0.3236
Echinococcus multilocularis	neuropeptides capa receptor	0.0053	0.3694	1
Echinococcus granulosus	neuropeptide s receptor	0.0053	0.3694	1
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0053	0.3694	1
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0053	0.3694	1
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0053	0.3694	0.2838
Echinococcus granulosus	neuropeptide Y receptor	0.0053	0.3694	1
Echinococcus multilocularis	g-protein coupled receptor	0.0053	0.3694	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.3694	1
Echinococcus granulosus	neuropeptide receptor	0.0053	0.3694	1
Schistosoma mansoni	biogenic amine receptor	0.0053	0.3694	0.2838
Schistosoma mansoni	opsin-like receptor	0.0053	0.3694	0.2838
Brugia malayi	hypothetical protein	0.0053	0.3694	0.2838
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0053	0.3694	1
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0053	0.3694	0.2838
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0053	0.3694	0.2838
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.004	0.1195	0.3236
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.3694	0.2838
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0053	0.3694	1
Echinococcus granulosus	sex peptide receptor	0.0053	0.3694	1
Echinococcus multilocularis	orexin receptor type 2	0.0053	0.3694	1
Echinococcus granulosus	g protein coupled receptor	0.0053	0.3694	1
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0053	0.3694	0.2838
Echinococcus multilocularis	neuropeptide receptor A26	0.0053	0.3694	1
Echinococcus granulosus	7tm_1 domain containing protein	0.0053	0.3694	1
Brugia malayi	hypothetical protein	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus granulosus	serotonin receptor	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Brugia malayi	neuropeptide F receptor	0.0053	0.3694	0.2838
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0053	0.3694	1
Echinococcus multilocularis	allatostatin A receptor	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0053	0.3694	1
Echinococcus granulosus	neuropeptide Y receptor	0.0053	0.3694	1
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0053	0.3694	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0053	0.3694	0.2838
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0053	0.3694	1
Schistosoma mansoni	amine GPCR	0.0053	0.3694	0.2838
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0053	0.3694	1
Onchocerca volvulus		0.0053	0.3694	0.2838
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0053	0.3694	0.2838
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0053	0.3694	1
Onchocerca volvulus		0.0053	0.3694	0.2838
Echinococcus multilocularis	g protein coupled receptor	0.0053	0.3694	1
Echinococcus granulosus	dro:myosuppressin receptor	0.0053	0.3694	1
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0053	0.3694	1
Brugia malayi	larval opioid receptor	0.0053	0.3694	0.2838
Echinococcus multilocularis	neuropeptide Y receptor	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.3694	1
Echinococcus granulosus	biogenic amine 5HT receptor	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Loa Loa (eye worm)	hypothetical protein	0.004	0.1195	0.1195
Echinococcus granulosus	neuropeptide FF receptor 2	0.0053	0.3694	1
Schistosoma mansoni	hypothetical protein	0.0086	1	1
Schistosoma mansoni	biogenic amine receptor	0.0053	0.3694	0.2838
Schistosoma mansoni	hypothetical protein	0.0053	0.3694	0.2838
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0053	0.3694	0.2838
Schistosoma mansoni	hypothetical protein	0.0053	0.3694	0.2838
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.3694	1
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0053	0.3694	0.2838
Echinococcus granulosus	neuropeptide receptor	0.0053	0.3694	1
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0053	0.3694	1
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0053	0.3694	0.2838
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0053	0.3694	0.2838
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0053	0.3694	0.3694
Schistosoma mansoni	myosin xvIII	0.0053	0.3694	0.2838
Schistosoma mansoni	neuropeptide f receptor 76f	0.0053	0.3694	0.2838
Echinococcus granulosus	orexin receptor type 2	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Brugia malayi	sulfakinin receptor protein	0.0053	0.3694	0.2838
Brugia malayi	hypothetical protein	0.0053	0.3694	0.2838
Echinococcus granulosus	7TM GPCR rhodopsin	0.0053	0.3694	1
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0053	0.3694	0.2838
Echinococcus granulosus	neuropeptide receptor A26	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.004	0.1195	0.3236
Loa Loa (eye worm)	neuropeptide F receptor	0.0053	0.3694	0.3694
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Schistosoma mansoni	adenoreceptor	0.0053	0.3694	0.2838
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.3694	1
Schistosoma mansoni	neuropeptide receptor	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus multilocularis	neuropeptides capa receptor	0.0053	0.3694	1
Brugia malayi	Dopamine receptor protein 1	0.0053	0.3694	0.2838
Echinococcus granulosus	g protein coupled receptor	0.0053	0.3694	1
Onchocerca volvulus		0.0053	0.3694	0.2838
Onchocerca volvulus		0.0053	0.3694	0.2838
Brugia malayi	putative neuropeptide receptor	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0053	0.3694	0.2838
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.3694	1
Brugia malayi	follicle stimulating hormone receptor	0.0053	0.3694	0.2838
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0053	0.3694	1
Echinococcus granulosus	neuropeptides capa receptor	0.0053	0.3694	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0053	0.3694	1
Echinococcus multilocularis	G protein coupled receptor 139	0.0053	0.3694	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.3694	1
Onchocerca volvulus		0.0053	0.3694	0.2838
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0053	0.3694	0.2838
Onchocerca volvulus		0.0053	0.3694	0.2838
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.3694	1
Brugia malayi	G protein-coupled receptor F59B2.13	0.0053	0.3694	0.2838
Schistosoma mansoni	opsin-like receptor	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.004	0.1195	0.1195
Echinococcus granulosus	fmrfamide receptor	0.0053	0.3694	1
Schistosoma mansoni	amine GPCR	0.0053	0.3694	0.2838
Schistosoma mansoni	amine GPCR	0.0053	0.3694	0.2838
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.3694	1
Echinococcus multilocularis	g protein coupled receptor	0.0053	0.3694	1
Echinococcus multilocularis	somatostatin receptor	0.0053	0.3694	1
Brugia malayi	hypothetical protein	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0053	0.3694	1
Onchocerca volvulus		0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0053	0.3694	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.3694	0.2838
Schistosoma mansoni	neuropeptide receptor	0.0053	0.3694	0.2838
Onchocerca volvulus		0.0053	0.3694	0.2838
Onchocerca volvulus		0.0053	0.3694	0.2838
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0053	0.3694	0.2838
Echinococcus granulosus	somatostatin receptor	0.0053	0.3694	1
Brugia malayi	G-protein coupled receptor	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus granulosus	biogenic amine 5HT receptor	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.3694	1
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus multilocularis	neuropeptide receptor	0.0053	0.3694	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0053	0.3694	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.3694	0.2838
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.004	0.1195	0.3236
Schistosoma mansoni	hypothetical protein	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.004	0.1195	0.3236
Schistosoma mansoni	hypothetical protein	0.0053	0.3694	0.2838
Onchocerca volvulus		0.0053	0.3694	0.2838
Echinococcus multilocularis	neuropeptide Y receptor	0.0053	0.3694	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Onchocerca volvulus		0.0053	0.3694	0.2838
Brugia malayi	hypothetical protein	0.0053	0.3694	0.2838
Schistosoma mansoni	neuropeptide F-like receptor	0.0053	0.3694	0.2838
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0053	0.3694	0.2838
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.3694	1
Onchocerca volvulus		0.0053	0.3694	0.2838
Brugia malayi	Serotonin receptor	0.0053	0.3694	0.2838
Brugia malayi	Dopamine receptor protein 2	0.0053	0.3694	0.2838
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.3694	0.2838
Loa Loa (eye worm)	G-protein coupled receptor	0.0053	0.3694	0.3694
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0053	0.3694	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.3694	1
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.004	0.1195	0.3236
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus multilocularis	dro:myosuppressin receptor	0.0053	0.3694	1
Brugia malayi	hypothetical protein	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus granulosus	allatostatin A receptor	0.0053	0.3694	1
Brugia malayi	G protein-coupled receptor	0.0053	0.3694	0.2838
Onchocerca volvulus		0.0053	0.3694	0.2838
Schistosoma mansoni	neuropeptide receptor	0.0053	0.3694	0.2838
Echinococcus granulosus	tm gpcr rhodopsin	0.0053	0.3694	1
Loa Loa (eye worm)	TYRA-2 protein	0.0053	0.3694	0.3694
Brugia malayi	RE15519p	0.0053	0.3694	0.2838
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0053	0.3694	1
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.004	0.1195	0.3236
Loa Loa (eye worm)	melatonin receptor type 1A	0.0053	0.3694	0.3694
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0053	0.3694	0.3694
Echinococcus granulosus	tm gpcr rhodopsin	0.0053	0.3694	1
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0053	0.3694	0.3694
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.3694	0.2838
Echinococcus multilocularis	fmrfamide receptor	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Schistosoma mansoni	growth hormone secretagogue receptor	0.0053	0.3694	0.2838
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0053	0.3694	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.3694	0.2838
Schistosoma mansoni	histamine h1 receptor	0.0053	0.3694	0.2838
Echinococcus granulosus	hypothetical protein	0.0053	0.3694	1
Brugia malayi	neuropeptide F receptor	0.0053	0.3694	0.2838
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.3694	0.2838
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0053	0.3694	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.3694	1
Brugia malayi	hypothetical protein	0.0053	0.3694	0.2838
Echinococcus multilocularis	serotonin receptor	0.0053	0.3694	1
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.004	0.1195	0.3236
Echinococcus multilocularis	sex peptide receptor	0.0053	0.3694	1
Schistosoma mansoni	amine GPCR	0.0053	0.3694	0.2838
Onchocerca volvulus		0.0053	0.3694	0.2838
Schistosoma mansoni	neuropeptide F-like receptor	0.0053	0.3694	0.2838
Brugia malayi	Melatonin receptor type 1A	0.0053	0.3694	0.2838
Schistosoma mansoni	neuropeptide receptor	0.0053	0.3694	0.2838
Loa Loa (eye worm)	G-protein coupled receptor	0.0053	0.3694	0.3694
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.004	0.1195	0.3236
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0053	0.3694	0.2838
Onchocerca volvulus		0.0053	0.3694	0.2838
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus granulosus	G protein coupled receptor 139	0.0053	0.3694	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Onchocerca volvulus		0.0086	1	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Schistosoma mansoni	biogenic amine receptor	0.0053	0.3694	0.2838
Echinococcus granulosus	g protein coupled receptor	0.0053	0.3694	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.004	0.1195	0.3236
Loa Loa (eye worm)	thrombospondin type 1 domain-containing protein	0.0086	1	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.3694	0.3694
Echinococcus granulosus	g-protein coupled receptor	0.0053	0.3694	1
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0053	0.3694	0.3694
Brugia malayi	hypothetical protein	0.0053	0.3694	0.2838
Loa Loa (eye worm)	neuropeptide F receptor	0.0053	0.3694	0.3694
Schistosoma mansoni	opsin-like receptor	0.0053	0.3694	0.2838
Echinococcus multilocularis	neuropeptide receptor	0.0053	0.3694	1
Schistosoma mansoni	amine GPCR	0.0053	0.3694	0.2838
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0053	0.3694	0.2838

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3349035

Bibliographic References

No literature references available for this target.

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Detailed information for compound 939273