Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | tubulin beta chain, putative | 0.0022 | 0.0065 | 1 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0022 | 0.0065 | 0.0299 |
Schistosoma mansoni | tyrosine kinase | 0.0063 | 0.0471 | 0.3537 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0022 | 0.0065 | 0.0299 |
Schistosoma mansoni | tyrosine kinase | 0.0138 | 0.1213 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0063 | 0.0471 | 0.3537 |
Leishmania major | telomerase reverse transcriptase, putative | 0.028 | 0.2624 | 1 |
Giardia lamblia | Telomerase catalytic subunit | 0.028 | 0.2624 | 1 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.028 | 0.2624 | 1 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.028 | 0.2624 | 1 |
Brugia malayi | Telomerase reverse transcriptase | 0.0746 | 0.7228 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0022 | 0.0065 | 1 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.028 | 0.2624 | 1 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.028 | 0.2624 | 1 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0063 | 0.0471 | 0.0567 |
Brugia malayi | Protein kinase domain containing protein | 0.0138 | 0.1213 | 0.1603 |
Echinococcus multilocularis | tubulin alpha chain | 0.0022 | 0.0065 | 0.0299 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0063 | 0.0471 | 0.3537 |
Loa Loa (eye worm) | alpha-tubulin | 0.0022 | 0.0065 | 0.0535 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0063 | 0.0471 | 0.3537 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0022 | 0.0065 | 1 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.028 | 0.2624 | 1 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0022 | 0.0065 | 0.0299 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0022 | 0.0065 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0063 | 0.0471 | 0.3537 |
Echinococcus multilocularis | tubulin alpha chain | 0.0022 | 0.0065 | 0.0299 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0022 | 0.0065 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0594 | 0.4895 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0017 | 0.0015 | 0.2326 |
Echinococcus multilocularis | tubulin subunit TubB | 0.0022 | 0.0065 | 0.0299 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0022 | 0.0065 | 0.0299 |
Echinococcus granulosus | insulin receptor | 0.0138 | 0.1213 | 1 |
Entamoeba histolytica | tubulin alpha-1 chain | 0.0022 | 0.0065 | 0.5 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0138 | 0.1213 | 1 |
Echinococcus multilocularis | peroxisome assembly protein 26 | 0.0022 | 0.0065 | 0.0299 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0022 | 0.0065 | 1 |
Echinococcus multilocularis | tubulin alpha chain | 0.0022 | 0.0065 | 0.0299 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0017 | 0.0015 | 0.0124 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0022 | 0.0065 | 0.0535 |
Echinococcus multilocularis | tubulin alpha chain | 0.0022 | 0.0065 | 0.0299 |
Schistosoma mansoni | tyrosine kinase | 0.0138 | 0.1213 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0061 | 0.046 | 0.3441 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0063 | 0.0471 | 0.3883 |
Schistosoma mansoni | tyrosine kinase | 0.0061 | 0.046 | 0.3441 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0065 | 0.0535 |
Schistosoma mansoni | tyrosine kinase | 0.0063 | 0.0471 | 0.3537 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0017 | 0.0015 | 0.0124 |
Echinococcus multilocularis | tubulin alpha chain | 0.0022 | 0.0065 | 0.0299 |
Loa Loa (eye worm) | alpha-tubulin | 0.0022 | 0.0065 | 0.0535 |
Entamoeba histolytica | tubulin alpha chain, putative | 0.0022 | 0.0065 | 0.5 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0022 | 0.0065 | 0.0535 |
Loa Loa (eye worm) | alpha-tubulin isotype 2 | 0.0017 | 0.0015 | 0.0124 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0138 | 0.1213 | 1 |
Echinococcus multilocularis | hypothetical protein | 0.0022 | 0.0065 | 0.0299 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0022 | 0.0065 | 0.0299 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0022 | 0.0065 | 0.0299 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0022 | 0.0065 | 1 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.028 | 0.2624 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0061 | 0.046 | 0.3441 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0015 | 0.0124 |
Loa Loa (eye worm) | tubulin alpha-2 chain | 0.0022 | 0.0065 | 0.0535 |
Echinococcus multilocularis | insulin receptor | 0.0138 | 0.1213 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0063 | 0.0471 | 0.373 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0063 | 0.0471 | 0.373 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0138 | 0.1213 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0022 | 0.0065 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0076 | 0.0605 | 0.0754 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0022 | 0.0065 | 1 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0022 | 0.0065 | 0.0299 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.