Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.2127 | 0.4428 | 0.5 |
Echinococcus granulosus | histone deacetylase 1 | 0.4644 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.4644 | 1 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4644 | 1 | 0.5 |
Schistosoma mansoni | histone deacetylase hda2 | 0.421 | 0.9038 | 0.8274 |
Loa Loa (eye worm) | histone deacetylase | 0.4148 | 0.8902 | 0.8902 |
Schistosoma mansoni | histone deacetylase | 0.4644 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.4148 | 0.8902 | 0.8029 |
Brugia malayi | histone deacetylase 11 | 0.3863 | 0.827 | 0.827 |
Echinococcus multilocularis | histone deacetylase 6 | 0.4148 | 0.8902 | 0.8029 |
Echinococcus granulosus | histone deacetylase 3 | 0.4644 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 3 | 0.4644 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.421 | 0.9038 | 0.8274 |
Plasmodium vivax | histone deacetylase 1, putative | 0.4644 | 1 | 1 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.4148 | 0.8902 | 0.8029 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4644 | 1 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.4644 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4644 | 1 | 0.5 |
Trypanosoma brucei | histone deacetylase 3 | 0.4148 | 0.8902 | 0.8029 |
Echinococcus multilocularis | histone deacetylase 7 | 0.4148 | 0.8902 | 0.8029 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.4644 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.4644 | 1 | 1 |
Trypanosoma brucei | histone deacetylase 1 | 0.4644 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.4644 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.3863 | 0.827 | 0.6895 |
Loa Loa (eye worm) | hypothetical protein | 0.1735 | 0.3561 | 0.3561 |
Brugia malayi | Histone deacetylase 1 | 0.4644 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.4148 | 0.8902 | 0.8029 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.3863 | 0.827 | 0.827 |
Plasmodium vivax | histone deacetylase, putative | 0.4148 | 0.8902 | 0.3655 |
Trypanosoma brucei | histone deacetylase, putative | 0.4148 | 0.8902 | 0.8029 |
Giardia lamblia | Histone deacetylase | 0.4644 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2083 | 0.433 | 0.433 |
Echinococcus granulosus | histone deacetylase 6 | 0.4148 | 0.8902 | 0.8029 |
Echinococcus granulosus | histone deacetylase 6 | 0.421 | 0.9038 | 0.8274 |
Schistosoma mansoni | histone deacetylase | 0.4644 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 1 | 0.4644 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4644 | 1 | 0.5 |
Echinococcus granulosus | histone deacetylase | 0.4148 | 0.8902 | 0.8029 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.4644 | 1 | 1 |
Plasmodium vivax | histone deacetylase 2, putative | 0.4148 | 0.8902 | 0.3655 |
Loa Loa (eye worm) | hypothetical protein | 0.4644 | 1 | 1 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.4644 | 1 | 1 |
Trypanosoma brucei | histone deacetylase 4 | 0.4148 | 0.8902 | 0.8029 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4644 | 1 | 0.5 |
Entamoeba histolytica | histone deacetylase, putative | 0.4644 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.4644 | 1 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.4148 | 0.8902 | 0.8902 |
Echinococcus granulosus | histone deacetylase 7 | 0.4148 | 0.8902 | 0.8029 |
Echinococcus multilocularis | histone deacetylase | 0.4148 | 0.8902 | 0.8029 |
Leishmania major | histone deacetylase, putative | 0.4644 | 1 | 1 |
Leishmania major | histone deacetylase, putative | 0.4644 | 1 | 1 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.4148 | 0.8902 | 0.8029 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.4644 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4644 | 1 | 0.5 |
Brugia malayi | Histone deacetylase family protein | 0.4148 | 0.8902 | 0.8902 |
Echinococcus granulosus | histone deacetylase 6 | 0.4148 | 0.8902 | 0.8029 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.4644 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2021 | 0.4194 | 0.4194 |
Loa Loa (eye worm) | hypothetical protein | 0.2127 | 0.4428 | 0.4428 |
Trypanosoma cruzi | histone deacetylase, putative | 0.4148 | 0.8902 | 0.8029 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.4148 | 0.8902 | 0.8902 |
Echinococcus multilocularis | histone deacetylase 6 | 0.4148 | 0.8902 | 0.8029 |
Plasmodium falciparum | histone deacetylase 1 | 0.4644 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.4148 | 0.8902 | 0.8029 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.