Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.0068 | 0.1414 | 1 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0068 | 0.1414 | 1 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.0073 | 0.1535 | 1 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0051 | 0.0988 | 0.5 |
Loa Loa (eye worm) | amidase | 0.0051 | 0.0988 | 0.0988 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0068 | 0.1414 | 1 |
Echinococcus granulosus | glutamyl tRNAGln amidotransferase subunit A | 0.0051 | 0.0988 | 0.0988 |
Schistosoma mansoni | transient receptor potential channel | 0.001 | 0.00000012788 | 0.00000012788 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.00000012788 | 0.00000012788 |
Brugia malayi | Amidase family protein | 0.0051 | 0.0988 | 0.0988 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.001 | 0.00000012788 | 0.00000012788 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0421 | 1 | 1 |
Plasmodium vivax | PST-A protein | 0.0068 | 0.1414 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0068 | 0.1414 | 1 |
Toxoplasma gondii | hypothetical protein | 0.001 | 0 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0068 | 0.1414 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0068 | 0.1414 | 1 |
Mycobacterium ulcerans | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD | 0.0405 | 0.9601 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0068 | 0.1414 | 1 |
Brugia malayi | putative amidase | 0.0051 | 0.0988 | 0.0988 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.001 | 0 | 0.5 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0421 | 1 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.001 | 0 | 0.5 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0421 | 1 | 1 |
Mycobacterium tuberculosis | 4,9-DHSA hydrolase | 0.0405 | 0.9601 | 1 |
Toxoplasma gondii | transporter, cation channel family protein | 0.001 | 0 | 0.5 |
Brugia malayi | Amidase family protein | 0.0051 | 0.0988 | 0.0988 |
Trypanosoma cruzi | amidase, putative | 0.0051 | 0.0988 | 0.6986 |
Mycobacterium ulcerans | lysophospholipase | 0.0068 | 0.1414 | 0.0495 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0421 | 1 | 1 |
Plasmodium falciparum | lysophospholipase, putative | 0.0068 | 0.1414 | 1 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.001 | 0 | 0.5 |
Toxoplasma gondii | transporter, cation channel family protein | 0.001 | 0 | 0.5 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.001 | 0 | 0.5 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0051 | 0.0988 | 0.5 |
Trypanosoma cruzi | amidase, putative | 0.0051 | 0.0988 | 0.6986 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0051 | 0.0988 | 0.0988 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0421 | 1 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.001 | 0.00000012788 | 0.00000012788 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0051 | 0.0988 | 0.0988 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0068 | 0.1414 | 1 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0051 | 0.0988 | 0.5 |
Brugia malayi | olfactory channel protein osm-9 | 0.001 | 0.00000012788 | 0.00000012788 |
Leishmania major | monoglyceride lipase, putative | 0.0068 | 0.1414 | 1 |
Plasmodium falciparum | lysophospholipase, putative | 0.0068 | 0.1414 | 1 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0068 | 0.1414 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.00000012788 | 0.00000012788 |
Plasmodium falciparum | esterase, putative | 0.0068 | 0.1414 | 1 |
Loa Loa (eye worm) | amidase | 0.0051 | 0.0988 | 0.0988 |
Toxoplasma gondii | hypothetical protein | 0.001 | 0 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.001 | 0.00000012788 | 0.00000012788 |
Schistosoma mansoni | transient receptor potential channel | 0.001 | 0.00000012788 | 0.00000012788 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0068 | 0.1414 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.00000012788 | 0.00000012788 |
Schistosoma mansoni | amidase | 0.0421 | 1 | 1 |
Trypanosoma brucei | fatty-acid amide hydrolase, putative | 0.0051 | 0.0988 | 0.6986 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.0068 | 0.1414 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0068 | 0.1414 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0068 | 0.1414 | 1 |
Echinococcus granulosus | transient receptor potential cation channel | 0.001 | 0.00000012788 | 0.00000012788 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.001 | 0.00000012788 | 0.00000012788 |
Leishmania major | hypothetical protein, conserved | 0.0051 | 0.0988 | 0.6986 |
Echinococcus multilocularis | glutamyl tRNA(Gln) amidotransferase subunit A | 0.0051 | 0.0988 | 0.0988 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 1 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0068 | 0.1414 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0051 | 0.0988 | 0.0988 |
Echinococcus granulosus | transient receptor potential cation channel | 0.001 | 0.00000012788 | 0.00000012788 |
Mycobacterium ulcerans | hypothetical protein | 0.0068 | 0.1414 | 0.0495 |
Mycobacterium tuberculosis | Possible lysophospholipase | 0.0073 | 0.1535 | 0.0636 |
Schistosoma mansoni | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0051 | 0.0988 | 0.0988 |
Toxoplasma gondii | transporter, cation channel family protein | 0.001 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.