Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | dynamin-like protein | 0.007 | 0.8159 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.007 | 0.8159 | 0.5 |
Leishmania major | GTP-binding protein, putative | 0.007 | 0.8159 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.007 | 0.8159 | 0.5 |
Toxoplasma gondii | dynamin-related protein DRPA | 0.007 | 0.8159 | 1 |
Schistosoma mansoni | dynamin | 0.0076 | 1 | 1 |
Giardia lamblia | Dynamin | 0.007 | 0.8159 | 0.5 |
Trypanosoma cruzi | dynamin-1-like protein | 0.007 | 0.8159 | 0.5 |
Trypanosoma brucei | dynamin-1-like protein | 0.007 | 0.8159 | 0.5 |
Trypanosoma brucei | dynamin-1-like protein | 0.007 | 0.8159 | 0.5 |
Echinococcus granulosus | dynamin 1 | 0.0076 | 1 | 1 |
Plasmodium falciparum | dynamin-like protein | 0.007 | 0.8159 | 0.5 |
Plasmodium vivax | dynamin protein, putative | 0.007 | 0.8159 | 0.5 |
Plasmodium vivax | dynamin-like protein, putative | 0.007 | 0.8159 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.007 | 0.8159 | 0.5 |
Echinococcus multilocularis | dynamin 1 | 0.0076 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 1 | 1 |
Toxoplasma gondii | dynamin-related protein DRPB | 0.007 | 0.8159 | 1 |
Trichomonas vaginalis | dynamin, putative | 0.007 | 0.8159 | 0.5 |
Schistosoma mansoni | dynamin | 0.0076 | 1 | 1 |
Brugia malayi | Dynamin | 0.0076 | 1 | 1 |
Entamoeba histolytica | dynamin-1-like protein, putative | 0.007 | 0.8159 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.007 | 0.8159 | 0.5 |
Plasmodium falciparum | dynamin-like protein | 0.007 | 0.8159 | 0.5 |
Trichomonas vaginalis | interferon-induced GTP-binding protein mx, putative | 0.007 | 0.8159 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.007 | 0.8159 | 0.5 |
Trichomonas vaginalis | mgm1, putative | 0.007 | 0.8159 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (ADMET) | = 2095 umol/L | Cytotoxicity against human WISH cells | ChEMBL. | 25515560 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.