Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | TAR-binding protein | 0.0072 | 0.2369 | 0.2369 |
Brugia malayi | RNA binding protein | 0.0072 | 0.2369 | 0.2369 |
Loa Loa (eye worm) | TAR-binding protein | 0.0072 | 0.2369 | 0.2369 |
Echinococcus multilocularis | acetylcholinesterase | 0.0136 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0136 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0072 | 0.2369 | 0.2369 |
Echinococcus granulosus | acetylcholinesterase | 0.0136 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0136 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.2369 | 0.2369 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0136 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.2369 | 0.2369 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.2369 | 0.2369 |
Echinococcus granulosus | tar DNA binding protein | 0.0072 | 0.2369 | 0.2369 |
Echinococcus granulosus | acetylcholinesterase | 0.0136 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0136 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0136 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.2369 | 0.2369 |
Brugia malayi | Carboxylesterase family protein | 0.0136 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0072 | 0.2369 | 0.2369 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.2369 | 0.2369 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0072 | 0.2369 | 0.2369 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0136 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0072 | 0.2369 | 0.2369 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 0.0000544 % | Measurement of binding affinity by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus | ChEMBL. | 7902439 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.