Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | phosphodiesterase 7A | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target/s | Ortholog Group |
---|---|---|---|
Echinococcus granulosus | high affinity cAMP specific 3'5' cyclic | Get druggable targets OG5_133100 | All targets in OG5_133100 |
Echinococcus multilocularis | high affinity cAMP specific 3',5' cyclic | Get druggable targets OG5_133100 | All targets in OG5_133100 |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cyclin B | 0.009 | 0.1503 | 0.2198 |
Echinococcus multilocularis | cyclin B | 0.009 | 0.1503 | 0.1397 |
Echinococcus multilocularis | high affinity cAMP specific 3',5' cyclic | 0.0468 | 1 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.019 | 0.3748 | 0.5778 |
Trichomonas vaginalis | cyclin B, putative | 0.009 | 0.1503 | 1 |
Plasmodium falciparum | cyclin | 0.0062 | 0.0857 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1503 | 0.2203 |
Trichomonas vaginalis | cyclin B, putative | 0.009 | 0.1503 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.009 | 0.1503 | 1 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.009 | 0.1503 | 1 |
Echinococcus multilocularis | cyclin B3 1 | 0.0062 | 0.0857 | 0.0744 |
Echinococcus granulosus | cyclin B | 0.009 | 0.1503 | 0.1397 |
Trichomonas vaginalis | cyclins, putative | 0.0062 | 0.0857 | 0.5706 |
Toxoplasma gondii | hypothetical protein | 0.0047 | 0.0524 | 1 |
Echinococcus multilocularis | cyclins | 0.0062 | 0.0857 | 0.0744 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.019 | 0.3748 | 0.367 |
Entamoeba histolytica | cyclin, putative | 0.0062 | 0.0857 | 0.5706 |
Trichomonas vaginalis | cyclin B, putative | 0.009 | 0.1503 | 1 |
Echinococcus granulosus | cyclins | 0.0062 | 0.0857 | 0.0744 |
Trichomonas vaginalis | cyclins, putative | 0.009 | 0.1503 | 1 |
Entamoeba histolytica | cyclin family protein | 0.0062 | 0.0857 | 0.5706 |
Echinococcus multilocularis | cyclins | 0.0062 | 0.0857 | 0.0744 |
Trichomonas vaginalis | cyclin A, putative | 0.009 | 0.1503 | 1 |
Echinococcus multilocularis | cyclin b3 | 0.0062 | 0.0857 | 0.0744 |
Trichomonas vaginalis | cyclins, putative | 0.0044 | 0.0453 | 0.3015 |
Echinococcus multilocularis | cyclins | 0.0062 | 0.0857 | 0.0744 |
Echinococcus granulosus | cyclins | 0.0062 | 0.0857 | 0.0744 |
Echinococcus multilocularis | cyclins | 0.0062 | 0.0857 | 0.0744 |
Entamoeba histolytica | cyclin family protein | 0.0062 | 0.0857 | 0.5706 |
Trichomonas vaginalis | cyclin B3, putative | 0.0062 | 0.0857 | 0.5706 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.019 | 0.3748 | 1 |
Entamoeba histolytica | cyclin, putative | 0.009 | 0.1503 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.009 | 0.1503 | 0.3806 |
Schistosoma mansoni | hypothetical protein | 0.0308 | 0.6399 | 1 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.019 | 0.3748 | 0.367 |
Trypanosoma cruzi | cyclin, putative | 0.009 | 0.1503 | 1 |
Trichomonas vaginalis | cyclin D, putative | 0.0062 | 0.0857 | 0.5706 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.009 | 0.1503 | 0.3806 |
Trichomonas vaginalis | cyclins, putative | 0.009 | 0.1503 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.0308 | 0.6399 | 0.6355 |
Trichomonas vaginalis | cyclin B, putative | 0.009 | 0.1503 | 1 |
Echinococcus granulosus | cyclins | 0.0062 | 0.0857 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1503 | 0.2203 |
Brugia malayi | RNA, U transporter 1 | 0.0082 | 0.1319 | 0.3299 |
Echinococcus multilocularis | cyclins | 0.0062 | 0.0857 | 0.0744 |
Echinococcus granulosus | cyclin b3 | 0.0062 | 0.0857 | 0.0744 |
Echinococcus granulosus | cyclin B3 1 | 0.0062 | 0.0857 | 0.0744 |
Trichomonas vaginalis | cyclins, putative | 0.009 | 0.1503 | 1 |
Echinococcus granulosus | cyclins | 0.0062 | 0.0857 | 0.0744 |
Onchocerca volvulus | 0.009 | 0.1503 | 0.5 | |
Trypanosoma cruzi | cyclin, putative | 0.009 | 0.1503 | 1 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.009 | 0.1503 | 1 |
Trichomonas vaginalis | cyclin D, putative | 0.0062 | 0.0857 | 0.5706 |
Echinococcus granulosus | snurportin 1 | 0.0308 | 0.6399 | 0.6355 |
Schistosoma mansoni | cyclin B3 | 0.019 | 0.3748 | 0.5776 |
Trypanosoma brucei | mitotic cyclin 6 | 0.009 | 0.1503 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0062 | 0.0857 | 0.5706 |
Schistosoma mansoni | cyclins | 0.0062 | 0.0857 | 0.1171 |
Trichomonas vaginalis | cyclin B, putative | 0.0062 | 0.0857 | 0.5706 |
Echinococcus multilocularis | cyclins | 0.0062 | 0.0857 | 0.0744 |
Echinococcus granulosus | cyclins | 0.0062 | 0.0857 | 0.0744 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0123 | 0.5 |
Trypanosoma cruzi | cyclin 6, putative | 0.009 | 0.1503 | 1 |
Leishmania major | cyclin | 0.009 | 0.1503 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0123 | 0.0006 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0308 | 0.6399 | 1 |
Echinococcus multilocularis | cyclins | 0.0062 | 0.0857 | 0.0744 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.009 | 0.1503 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.