Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0005 | 0 | 0.5 | |
Entamoeba histolytica | protein kinase, putative | 0.0013 | 0.2467 | 0.3189 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.819 | 0.819 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0037 | 1 | 1 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0008 | 0.1118 | 0.1118 |
Trypanosoma cruzi | myosin heavy chain kinase A, putative | 0.0031 | 0.819 | 0.5 |
Onchocerca volvulus | 0.0005 | 0 | 0.5 | |
Schistosoma mansoni | eukaryotic elongation factor 2 kinase (eef-2 kinase) | 0.0031 | 0.819 | 0.819 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0007 | 0.0796 | 0.0796 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0009 | 0.1349 | 0.1744 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0007 | 0.0796 | 0.0796 |
Loa Loa (eye worm) | TK protein kinase | 0.003 | 0.7735 | 0.7735 |
Trypanosoma cruzi | myosin heavy chain kinase A, putative | 0.0031 | 0.819 | 0.5 |
Onchocerca volvulus | 0.0005 | 0 | 0.5 | |
Loa Loa (eye worm) | TK protein kinase | 0.0033 | 0.8882 | 0.8882 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0037 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0008 | 0.1118 | 0.1118 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0037 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0037 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0037 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0009 | 0.1349 | 0.1744 |
Brugia malayi | Variant SH3 domain containing protein | 0.0007 | 0.0796 | 0.0796 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0037 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0037 | 1 | 1 |
Schistosoma mansoni | elongation factor 2 kinase | 0.0009 | 0.1349 | 0.1349 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0032 | 0.856 | 0.856 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0037 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0037 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0033 | 0.8882 | 0.8882 |
Entamoeba histolytica | elongation factor-2 kinase, putative | 0.0009 | 0.1349 | 0.1744 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0037 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0009 | 0.1349 | 0.1744 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0007 | 0.0796 | 0.0796 |
Trypanosoma brucei | myosin heavy chain kinase A, putative | 0.0031 | 0.819 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0009 | 0.1349 | 0.1744 |
Entamoeba histolytica | hypothetical protein | 0.0009 | 0.1349 | 0.1744 |
Brugia malayi | Variant SH3 domain containing protein | 0.0007 | 0.0796 | 0.0796 |
Trypanosoma brucei | myosin heavy chain kinase A, putative | 0.0031 | 0.819 | 0.5 |
Loa Loa (eye worm) | SRC-1 | 0.0037 | 1 | 1 |
Onchocerca volvulus | 0.0005 | 0 | 0.5 | |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0007 | 0.0796 | 0.0796 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0007 | 0.0796 | 0.0796 |
Entamoeba histolytica | hypothetical protein | 0.0009 | 0.1349 | 0.1744 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0037 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0033 | 0.8882 | 0.8882 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0037 | 1 | 1 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0007 | 0.0796 | 0.0796 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0008 | 0.1118 | 0.1118 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0037 | 1 | 1 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0009 | 0.1349 | 0.1744 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0008 | 0.1118 | 0.1118 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0037 | 1 | 1 |
Echinococcus granulosus | tyrosine kinase | 0.0033 | 0.8882 | 0.8882 |
Schistosoma mansoni | elongation factor 2 kinase | 0.0009 | 0.1349 | 0.1349 |
Brugia malayi | MHCK/EF2 kinase domain family protein | 0.0031 | 0.819 | 0.819 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0037 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0009 | 0.1349 | 0.1744 |
Brugia malayi | protein-tyrosine kinase | 0.0033 | 0.8882 | 0.8882 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0033 | 0.8882 | 0.8882 |
Echinococcus granulosus | NCK adaptor protein | 0.0007 | 0.0796 | 0.0796 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0033 | 0.8882 | 0.8882 |
Entamoeba histolytica | protein kinase, putative | 0.003 | 0.7735 | 1 |
Echinococcus granulosus | c src tyrosine kinase | 0.0008 | 0.1118 | 0.1118 |
Onchocerca volvulus | 0.0005 | 0 | 0.5 | |
Entamoeba histolytica | hypothetical protein | 0.0009 | 0.1349 | 0.1744 |
Echinococcus multilocularis | eukaryotic elongation factor 2 kinase | 0.0031 | 0.819 | 0.819 |
Schistosoma mansoni | tyrosine kinase | 0.0037 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0796 | 0.0796 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0037 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0008 | 0.1118 | 0.1118 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.003 | 0.7735 | 0.7735 |
Entamoeba histolytica | hypothetical protein | 0.0009 | 0.1349 | 0.1744 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0008 | 0.1118 | 0.1118 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0008 | 0.1118 | 0.1118 |
Echinococcus granulosus | eukaryotic elongation factor 2 kinase | 0.0031 | 0.819 | 0.819 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0007 | 0.0796 | 0.0796 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0008 | 0.1118 | 0.1118 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0033 | 0.8882 | 0.8882 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0037 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0037 | 1 | 1 |
Onchocerca volvulus | 0.0005 | 0 | 0.5 | |
Schistosoma mansoni | adapter molecule crk | 0.0007 | 0.0796 | 0.0796 |
Leishmania major | myosin heavy chain kinase a-like protein | 0.0031 | 0.819 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0009 | 0.1349 | 0.1744 |
Schistosoma mansoni | nck2/grb4 | 0.0007 | 0.0796 | 0.0796 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0032 | 0.856 | 0.856 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0007 | 0.0796 | 0.0796 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.003 | 0.7735 | 0.7735 |
Echinococcus multilocularis | NCK adaptor protein | 0.0007 | 0.0796 | 0.0796 |
Entamoeba histolytica | hypothetical protein | 0.0009 | 0.1349 | 0.1744 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.