Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0202 | 1 | 1 |
Plasmodium vivax | protein kinase Crk2 | 0.0202 | 1 | 1 |
Mycobacterium tuberculosis | Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) | 0.0164 | 0.7842 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0202 | 1 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0202 | 1 | 1 |
Mycobacterium leprae | Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) | 0.0188 | 0.921 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.9879 | 0.9879 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0202 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0202 | 1 | 1 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0202 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0202 | 1 | 1 |
Chlamydia trachomatis | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0174 | 0.8422 | 0.5 |
Plasmodium falciparum | protein kinase 5 | 0.0202 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0188 | 0.921 | 0.5 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0202 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0202 | 1 | 1 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0202 | 1 | 1 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0202 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0122 | 0.5516 | 0.599 |
Echinococcus granulosus | cyclin dependent kinase | 0.0202 | 1 | 1 |
Treponema pallidum | hypothetical protein | 0.0188 | 0.921 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0202 | 1 | 1 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0202 | 1 | 1 |
Mycobacterium ulcerans | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0188 | 0.921 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0202 | 1 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0202 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0202 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0202 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0202 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0202 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0202 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0202 | 1 | 1 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0202 | 1 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.0202 | 1 | 1 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0202 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0202 | 1 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0202 | 1 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0202 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.