TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 300.261 | Formula: C13H16O8
H donors: 5 H acceptors: 6 LogP: -0.71 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: OC[C@H]1O[C@@H](OC(=O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O
InChi: 1S/C13H16O8/c14-5-8-9(16)10(17)11(18)13(20-8)21-12(19)6-1-3-7(15)4-2-6/h1-4,8-11,13-18H,5H2/t8-,9-,10+,11-,13+/m1/s1
InChiKey: XWTGDGASXRARSP-HMUNZLOLSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	amine GPCR	0.0132	0.0065	0.0065
Brugia malayi	putative neuropeptide receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Onchocerca volvulus		0.0132	0.0065	1
Echinococcus multilocularis	expressed conserved protein	0.0073	0.0024	0.0024
Brugia malayi	hypothetical protein	0.0187	0.0103	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus granulosus	Niemann Pick C1 protein	0.0111	0.0051	0.0027
Echinococcus multilocularis	g protein coupled receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0132	0.0065	0.0065
Brugia malayi	hypothetical protein	0.0132	0.0065	0.0065
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0132	0.0065	0.0065
Echinococcus multilocularis	neuropeptide receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	hypothetical protein	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus granulosus	neuropeptide Y receptor	0.0132	0.0065	0.0041
Echinococcus multilocularis	allatostatin A receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0132	0.0065	0.0065
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.0114	0.0052	1
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0132	0.0065	0.0065
Echinococcus granulosus	neuropeptide receptor A26	0.0496	0.0318	0.0294
Echinococcus multilocularis	g protein coupled receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	atpase aaa+ type core atpase aaa type core	0.0641	0.0419	0.0419
Echinococcus granulosus	rhodopsin orphan GPCR	0.0132	0.0065	0.0041
Echinococcus granulosus	7tm_1 domain containing protein	0.0132	0.0065	0.0041
Echinococcus granulosus	alpha 16 mannosyl glycoprotein	1.4439	1	1
Echinococcus granulosus	fmrfamide receptor	0.0132	0.0065	0.0041
Brugia malayi	GnHR receptor homolog	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0114	0.0052	1
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0132	0.0065	0.0065
Echinococcus granulosus	neuropeptides capa receptor	0.0132	0.0065	0.0041
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0132	0.0065	0.0041
Schistosoma mansoni	neuropeptide receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	g-protein coupled receptor	0.0132	0.0065	0.0065
Echinococcus granulosus	g protein coupled receptor	0.0132	0.0065	0.0041
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Schistosoma mansoni	amine GPCR	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus granulosus	rhodopsin orphan GPCR	0.0132	0.0065	0.0041
Schistosoma mansoni	neuropeptide F-like receptor	0.0132	0.0065	0.0065
Wolbachia endosymbiont of Brugia malayi	ATP-dependent Clp protease proteolytic subunit	0.0114	0.0052	0.5
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0132	0.0065	0.0063
Echinococcus granulosus	G protein coupled receptor 139	0.0132	0.0065	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0114	0.0052	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0132	0.0065	0.0065
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0132	0.0065	0.0063
Loa Loa (eye worm)	G-protein coupled receptor	0.0132	0.0065	0.0063
Entamoeba histolytica	Niemann-Pick C1 protein, putative	0.0078	0.0028	0.5
Echinococcus multilocularis	Niemann Pick C1 protein	0.0111	0.0051	0.0051
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Schistosoma mansoni	growth hormone secretagogue receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	neuropeptides capa receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0132	0.0065	0.0065
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	hypothetical protein	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0254	0.015	0.0148
Brugia malayi	Serotonin receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0132	0.0065	0.0065
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0132	0.0065	0.0065
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0132	0.0065	0.0065
Onchocerca volvulus		0.0132	0.0065	1
Schistosoma mansoni	histamine h1 receptor	0.0132	0.0065	0.0065
Brugia malayi	Dopamine receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	neuropeptide receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0132	0.0065	0.0065
Brugia malayi	ORL1-like opioid receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	orexin receptor type 2	0.0132	0.0065	0.0065
Schistosoma mansoni	myosin xvIII	0.0132	0.0065	0.0065
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0132	0.0065	0.0065
Brugia malayi	putative neuropeptide receptor NPR1	0.0132	0.0065	0.0065
Brugia malayi	hypothetical protein	0.0132	0.0065	0.0065
Echinococcus granulosus	rhodopsin orphan GPCR	0.0132	0.0065	0.0041
Echinococcus granulosus	somatostatin receptor	0.0132	0.0065	0.0041
Loa Loa (eye worm)	neuropeptide F receptor	0.0132	0.0065	0.0063
Brugia malayi	G protein-coupled receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	sex peptide receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP)	0.0074	0.0025	0.5
Echinococcus granulosus	neuropeptide Y receptor	0.0132	0.0065	0.0041
Echinococcus multilocularis	peptidase Clp (S14 family)	0.0074	0.0025	0.0025
Schistosoma mansoni	adenoreceptor	0.0132	0.0065	0.0065
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0132	0.0065	0.0065
Schistosoma mansoni	amine GPCR	0.0132	0.0065	0.0065
Echinococcus multilocularis	fmrfamide receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	opsin-like receptor	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus multilocularis	neuropeptide receptor	0.0132	0.0065	0.0065
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0132	0.0065	0.0041
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0114	0.0052	0.5
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus multilocularis	serotonin receptor	0.0254	0.015	0.015
Echinococcus granulosus	hypothetical protein	0.0132	0.0065	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Treponema pallidum	ATP-dependent Clp protease proteolytic subunit	0.0114	0.0052	1
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	neuropeptide Y receptor	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Loa Loa (eye worm)	melatonin receptor type 1A	0.0132	0.0065	0.0063
Onchocerca volvulus		0.0132	0.0065	1
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0132	0.0065	0.0041
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0132	0.0065	0.0065
Brugia malayi	Dopamine receptor protein 1	0.0132	0.0065	0.0065
Onchocerca volvulus		0.0132	0.0065	1
Echinococcus multilocularis	somatostatin receptor	0.0132	0.0065	0.0065
Brugia malayi	Serotonin receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0132	0.0065	0.0065
Echinococcus multilocularis	Niemann Pick C1 protein	0.0078	0.0028	0.0028
Brugia malayi	G protein-coupled receptor F59B2.13	0.0132	0.0065	0.0065
Schistosoma mansoni	biogenic amine receptor	0.0132	0.0065	0.0065
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0132	0.0065	0.0063
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	neuropeptide receptor	0.0132	0.0065	0.0065
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0132	0.0065	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Onchocerca volvulus		0.0132	0.0065	1
Brugia malayi	sulfakinin receptor protein	0.0132	0.0065	0.0065
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0132	0.0065	0.0041
Echinococcus multilocularis	dro:myosuppressin receptor	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0254	0.015	0.0148
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus granulosus	neuropeptide FF receptor 2	0.0132	0.0065	0.0041
Schistosoma mansoni	hypothetical protein	0.0132	0.0065	0.0065
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0132	0.0065	0.0065
Brugia malayi	follicle stimulating hormone receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	neuropeptide Y receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	amine GPCR	0.426	0.2932	0.2932
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0132	0.0065	0.0065
Schistosoma mansoni	amine GPCR	0.0132	0.0065	0.0065
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0132	0.0065	0.0065
Brugia malayi	AKH receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	neuropeptide s receptor	0.0496	0.0318	0.0318
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus granulosus	rhodopsin orphan GPCR	0.0132	0.0065	0.0041
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0132	0.0065	0.0065
Echinococcus multilocularis	ATP dependent Clp protease proteolytic subunit	0.0114	0.0052	0.0052
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0114	0.0052	0.5
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0132	0.0065	0.0065
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0132	0.0065	0.0065
Echinococcus granulosus	g protein coupled receptor	0.0132	0.0065	0.0041
Echinococcus granulosus	ATP dependent Clp protease proteolytic subunit	0.0114	0.0052	0.0028
Echinococcus granulosus	tm gpcr rhodopsin	0.0132	0.0065	0.0041
Brugia malayi	hypothetical protein	0.0132	0.0065	0.0065
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0132	0.0065	0.0065
Schistosoma mansoni	niemann-pick C1 (NPC1)	0.0079	0.0028	0.0028
Onchocerca volvulus		0.0132	0.0065	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0132	0.0065	0.0065
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2)	0.0114	0.0052	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0132	0.0065	0.0065
Onchocerca volvulus		0.0132	0.0065	1
Schistosoma mansoni	neuropeptide receptor	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus multilocularis	G protein coupled receptor 139	0.0132	0.0065	0.0065
Echinococcus granulosus	orexin receptor type 2	0.0132	0.0065	0.0041
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0132	0.0065	0.0065
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0132	0.0065	0.0065
Echinococcus granulosus	tm gpcr rhodopsin	0.0132	0.0065	0.0041
Schistosoma mansoni	hypothetical protein	0.0132	0.0065	0.0065
Brugia malayi	Dopamine receptor protein 2	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0132	0.0065	0.0041
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	alpha 1,6 mannosyl glycoprotein	1.4439	1	1
Onchocerca volvulus		0.0132	0.0065	1
Brugia malayi	hypothetical protein	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Brugia malayi	hypothetical protein	0.0132	0.0065	0.0065
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0132	0.0065	0.0065
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0132	0.0065	0.0063
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0132	0.0065	0.0041
Brugia malayi	neuropeptide F receptor	0.0132	0.0065	0.0065
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0132	0.0065	0.0063
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2)	0.0074	0.0025	0.5
Echinococcus granulosus	dro:myosuppressin receptor	0.0132	0.0065	0.0041
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0132	0.0065	0.0041
Brugia malayi	hypothetical protein	0.0132	0.0065	0.0065
Brugia malayi	Niemann-Pick C1 protein precursor	0.0078	0.0028	0.0028
Echinococcus granulosus	survival motor neuron protein 1	0.0187	0.0103	0.0079
Onchocerca volvulus		0.0132	0.0065	1
Loa Loa (eye worm)	neuropeptide F receptor	0.0132	0.0065	0.0063
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0132	0.0065	0.0065
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0132	0.0065	0.0065
Onchocerca volvulus		0.0132	0.0065	1
Brugia malayi	Melatonin receptor type 1A	0.0132	0.0065	0.0065
Onchocerca volvulus		0.0132	0.0065	1
Echinococcus granulosus	neuropeptide s receptor	0.0496	0.0318	0.0294
Loa Loa (eye worm)	hypothetical protein	0.0187	0.0103	0.0101
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0132	0.0065	1
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0132	0.0065	0.0065
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Loa Loa (eye worm)	TYRA-2 protein	0.0132	0.0065	0.0063
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Schistosoma mansoni	opsin-like receptor	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus granulosus	biogenic amine 5HT receptor	0.0132	0.0065	0.0041
Echinococcus granulosus	tm gpcr rhodopsin	0.0132	0.0065	0.0041
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0132	0.0065	0.0065
Onchocerca volvulus		0.0132	0.0065	1
Schistosoma mansoni	opsin-like receptor	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Schistosoma mansoni	neuropeptide f receptor 76f	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0132	0.0065	0.0065
Brugia malayi	G-protein coupled receptor	0.0132	0.0065	0.0065
Echinococcus granulosus	serotonin receptor	0.0132	0.0065	0.0041
Schistosoma mansoni	neuropeptide F-like receptor	0.0132	0.0065	0.0065
Echinococcus granulosus	sex peptide receptor	0.0132	0.0065	0.0041
Brugia malayi	hypothetical protein	0.0132	0.0065	0.0065
Echinococcus multilocularis	fmrfamide receptor	0.0132	0.0065	0.0065
Brugia malayi	hypothetical protein	0.0132	0.0065	0.0065
Echinococcus granulosus	allatostatin A receptor	0.0132	0.0065	0.0041
Onchocerca volvulus		0.0132	0.0065	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Schistosoma mansoni	biogenic amine receptor	0.0132	0.0065	0.0065
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP)	0.0074	0.0025	0.4744
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus granulosus	g-protein coupled receptor	0.0132	0.0065	0.0041
Brugia malayi	G-protein coupled receptor	0.0132	0.0065	0.0065
Echinococcus granulosus	rhodopsin orphan GPCR	0.0132	0.0065	0.0041
Echinococcus granulosus	rhodopsin orphan GPCR	0.0132	0.0065	0.0041
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0132	0.0065	0.0065
Echinococcus multilocularis	survival motor neuron protein 1	0.0187	0.0103	0.0103
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0132	0.0065	1
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Schistosoma mansoni	biogenic amine receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	serotonin receptor	0.0254	0.015	0.015
Echinococcus multilocularis	g protein coupled receptor	0.0132	0.0065	0.0065
Echinococcus granulosus	neuropeptides capa receptor	0.0132	0.0065	0.0041
Onchocerca volvulus		0.0132	0.0065	1
Echinococcus multilocularis	neuropeptide receptor A26	0.0496	0.0318	0.0318
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0132	0.0065	0.0065
Echinococcus granulosus	Niemann Pick C1 protein	0.0078	0.0028	0.0003
Brugia malayi	RE15519p	0.0132	0.0065	0.0065
Echinococcus granulosus	7TM GPCR rhodopsin	0.0132	0.0065	0.0041
Echinococcus granulosus	biogenic amine 5HT receptor	0.0254	0.015	0.0126
Echinococcus granulosus	neuropeptide receptor	0.0132	0.0065	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Schistosoma mansoni	peptidase Clp (S14 family)	0.0114	0.0052	0.0052
Echinococcus granulosus	peptidase Clp S14 family	0.0074	0.0025	0.0001
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Schistosoma mansoni	beta-12-n-acetylglucosaminyltransferase II	1.4439	1	1
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Brugia malayi	hypothetical protein	0.0132	0.0065	0.0065
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0132	0.0065	0.0065
Brugia malayi	larval opioid receptor	0.0132	0.0065	0.0065
Onchocerca volvulus		0.0132	0.0065	1
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0132	0.0065	0.0065
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0132	0.0065	0.0065
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0132	0.0065	0.0065
Onchocerca volvulus		0.0132	0.0065	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0132	0.0065	0.0065
Loa Loa (eye worm)	G-protein coupled receptor	0.0132	0.0065	0.0063
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0254	0.015	0.015
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus granulosus	rhodopsin orphan GPCR	0.0132	0.0065	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0132	0.0065	0.0041
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0114	0.0052	0.5
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0052	0.005
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0114	0.0052	1
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0114	0.0052	1
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Brugia malayi	Probable ClpP-like protease	0.0114	0.0052	0.0052
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0065	0.0063
Brugia malayi	hypothetical protein	0.0132	0.0065	0.0065
Loa Loa (eye worm)	hypothetical protein	1.4439	1	1
Onchocerca volvulus		0.0132	0.0065	1
Echinococcus granulosus	g protein coupled receptor	0.0132	0.0065	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0028	0.0026
Echinococcus multilocularis	neuropeptides capa receptor	0.0132	0.0065	0.0065
Echinococcus granulosus	neuropeptide receptor	0.0132	0.0065	0.0041
Brugia malayi	neuropeptide F receptor	0.0132	0.0065	0.0065

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL482044

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 985837