Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | 1,3-beta-glucan synthase component protein | 0.0628 | 0.4549 | 1 |
Schistosoma mansoni | family A2 unassigned peptidase (A02 family) | 0.0226 | 0.0983 | 0.0983 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0115 | 0 | 0.5 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0115 | 0 | 0.5 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0115 | 0 | 0.5 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0115 | 0 | 0.5 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0115 | 0 | 0.5 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0115 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.